:root{--bg:#f7f7f1;--surface:#fff;--ink:#253d37;--muted:#64726b;--line:#dfe4da;--green:#205c4f;--pale:#eaf2e8;--human:#2c6d5e;--pre:#557a9b;--theory:#8e6a9d;--anec:#a77032;--unknown:#7a817a;font-family:Inter,ui-sans-serif,-apple-system,BlinkMacSystemFont,"Segoe UI",sans-serif;font-size:14px;color:var(--ink);background:var(--bg);font-synthesis:none}*{box-sizing:border-box}body{margin:0}button,input,select{font:inherit}button,a,select{touch-action:manipulation}button{cursor:pointer}a{color:var(--green)}button{color:inherit}button:focus-visible,a:focus-visible,input:focus-visible,select:focus-visible{outline:3px solid #719f65;outline-offset:3px}svg{width:20px;height:20px;fill:none;stroke:currentColor;stroke-width:1.7}button{border:0;background:transparent}.topbar{height:82px;display:flex;align-items:center;gap:45px;padding:0 4%;border-bottom:1px solid var(--line);background:#fcfcf8}.brand{display:flex;gap:12px;align-items:center;text-decoration:none;font-size:11px;font-weight:750;letter-spacing:1.6px;color:var(--ink)}.brandmark{width:40px;height:42px;background:var(--green);color:#f5f8e9;font-family:Georgia,serif;font-size:38px;line-height:30px;padding-left:10px;border-radius:12px 12px 12px 3px;letter-spacing:-5px}.brandmark span{color:#b7d4a4}.brand small{display:block;font-size:10px;font-weight:450;letter-spacing:.25px;margin-top:5px;color:var(--muted)}nav{align-self:stretch;display:flex;gap:28px;margin-left:25px}.navitem{height:100%;font-size:13px;border-bottom:3px solid transparent;padding:0 1px;color:var(--muted)}.navitem.active{color:var(--green);border-color:var(--green);font-weight:650}.private{display:flex;align-items:center;gap:7px;margin-left:auto;font-size:11px;font-weight:600;padding:7px 11px;background:#e9f0e5;border:1px solid #d7e3d1;border-radius:20px}.private svg{width:14px;height:14px}main{max-width:1680px;margin:auto;padding:0 4%}.intro{display:flex;align-items:center;justify-content:space-between;gap:24px;padding:35px 0 27px}.eyebrow{font-size:10px;letter-spacing:1.6px;font-weight:700;color:var(--green);margin-bottom:12px}h1{font:40px/1.12 Georgia,"Times New Roman",serif;letter-spacing:-1.2px;margin:0;color:#233f35;font-weight:400}.edition{display:inline-block;font:10px Inter,sans-serif;letter-spacing:1px;border:1px solid #bdccba;padding:5px 6px;border-radius:5px;vertical-align:top;margin:5px 0 0 12px;color:#668261}.intro p{color:var(--muted);margin:12px 0 0;line-height:1.5}.snapshot{position:relative;padding-left:18px;font-size:11px;line-height:1.6;color:var(--muted)}.snapshot strong{display:block;color:var(--ink);font-weight:600}.snapshot>span:not(.status-dot){display:block}.status-dot{position:absolute;left:0;top:7px;width:6px;height:6px;background:#78986a;border-radius:50%}.textbutton{font-size:11px;color:var(--green);padding:4px 0;text-decoration:underline;text-underline-offset:3px}.overview{display:flex;align-items:center;gap:23px;padding:16px 0;border-top:1px solid var(--line);border-bottom:1px solid var(--line);font-size:11px;color:var(--muted)}.overview strong{font-size:16px;font-weight:600;color:var(--ink);margin-right:3px}.legend{margin-left:auto;display:flex;gap:15px}.legend>span{display:flex;align-items:center;gap:5px}.dot{width:7px;height:7px;display:inline-block;border-radius:50%;background:var(--unknown);flex-shrink:0}.dot.H{background:var(--human)}.dot.P{background:var(--pre)}.dot.T{background:var(--theory)}.dot.A{background:var(--anec)}.dot.U{background:var(--unknown)}.searchbar{display:flex;align-items:center;gap:15px;padding:24px 0 20px}.searchwrap{background:var(--surface);border:1px solid #d6ded3;border-radius:7px;height:46px;display:flex;align-items:center;gap:12px;padding:0 15px;max-width:720px;width:100%;box-shadow:0 2px 4px #263b3010}.searchwrap svg{color:#7a8a7c;width:18px}.searchwrap input{border:0;outline:none;min-width:0;width:100%;font-size:13px;background:transparent;color:var(--ink)}.searchwrap input::placeholder{color:#7a857d}kbd{border:1px solid var(--line);color:#9aa395;font:11px monospace;border-radius:3px;padding:2px 5px}.subtle{font-size:12px;color:var(--muted);padding:8px 4px;text-decoration:underline;text-underline-offset:4px}.layout{display:grid;grid-template-columns:210px minmax(270px,340px) minmax(0,1fr);align-items:start;border-top:1px solid var(--line);min-height:690px}.filters{padding:23px 22px 20px 0}.filterheading{font-size:10px;font-weight:700;letter-spacing:1.3px;display:flex;justify-content:space-between;margin:0 0 12px;color:#71806e}.filterheading span{font-size:10px;letter-spacing:0}.pathbutton{width:100%;display:flex;align-items:center;justify-content:space-between;text-align:left;gap:6px;border-radius:6px;padding:10px 9px;font-size:11px;color:#606e61;margin:2px 0}.pathbutton:hover{background:#eef1e9}.pathbutton.selected{background:#e3eddf;color:#2c5b42;font-weight:650}.pathbutton .count{font-size:10px;opacity:.7}.filtergroup{margin-top:20px}.filtergroup label{display:block;font-size:11px;font-weight:600;margin-bottom:7px}.filtergroup select{width:100%;border:1px solid #d5ded0;border-radius:5px;background:#fcfcf8;color:#415547;font-size:11px;padding:9px 5px;min-height:36px}.filter-note{font-size:10px;line-height:1.7;color:#7a8476;margin-top:22px}.catalog{border-left:1px solid var(--line);border-right:1px solid var(--line);min-height:100%;background:#fbfcf8}.cataloghead{display:flex;justify-content:space-between;align-items:center;padding:23px 19px 18px}.cataloghead h2{font-size:13px;margin:0;font-weight:650}.cataloghead span{font-size:10px;color:var(--muted)}.cataloglabels{display:flex;justify-content:space-between;gap:10px;padding:0 19px 11px;border-bottom:1px solid var(--line);font-size:8px;color:#7d897b;letter-spacing:.8px}.compoundrow{display:block;text-align:left;width:100%;border-bottom:1px solid #e4e9df;padding:17px 19px;border-left:3px solid transparent;min-height:89px}.compoundrow:hover{background:#eef2e8}.compoundrow.selected{background:#eaf1e4;border-left-color:var(--green)}.rowtop{display:flex;align-items:center;gap:6px;justify-content:space-between}.rowtop strong{font-size:13px;font-weight:650}.tierdots{display:flex;align-items:center;gap:5px}.rowpath{display:block;color:#76816f;font-size:9px;margin-top:7px;letter-spacing:.25px}.rowmeta{display:block;font-size:9px;color:#7c8775;margin-top:6px}.detail{padding:26px 0 35px 28px;min-width:0}.detailpath{font-size:10px;letter-spacing:1px;color:#738269;text-transform:uppercase}.detail h2{font:30px/1.2 Georgia,serif;font-weight:400;margin:9px 0 12px;letter-spacing:-.5px}.compoundtype{display:inline-block;font-size:9px;font-weight:600;color:#698160;background:#e9eee3;border:1px solid #d9e2d1;border-radius:4px;padding:4px 7px;vertical-align:middle;margin:0 0 4px 7px;font-family:Inter,sans-serif;letter-spacing:0}.target{font-size:12px;line-height:1.6;color:#536650;margin:0}.detailtools{display:flex;gap:15px;flex-wrap:wrap;margin-top:12px}.detailtools button{font-size:10px;text-decoration:underline;text-underline-offset:3px;color:#6b8062;padding:0}.gap{background:#f0f2e9;border-left:2px solid #8b9a71;padding:12px 14px;margin:20px 0;font-size:11px;line-height:1.7;color:#657056}.gap strong{font-size:9px;display:block;letter-spacing:.8px;margin-bottom:4px;color:#536247}.tabs{display:flex;border-bottom:1px solid var(--line);gap:20px;margin:19px 0 19px}.tab{padding:0 0 12px;border-bottom:2px solid transparent;color:#6e7d69;font-size:11px}.tab.active{border-color:var(--green);color:var(--green);font-weight:650}.matchnote{font-size:10px;color:#788571;margin:10px 0 19px;line-height:1.6}.record{border:1px solid var(--line);border-radius:7px;background:var(--surface);padding:17px;margin:12px 0}.recordtop{display:flex;flex-wrap:wrap;gap:7px;align-items:center}.badge{font-size:9px;padding:4px 7px;border-radius:4px;font-weight:600;display:inline-block;background:#edf0e9;color:#6e766d}.badge.H{color:#245e4f;background:#e2eee7}.badge.P{color:#45647f;background:#e9eff5}.badge.T{color:#795489;background:#f2eaf5}.badge.A{color:#8e5c22;background:#fbefdf}.badge.U{color:#6c746a;background:#eef0ea}.strength{font-size:9px;color:#8a9184}.record h3{font-size:13px;line-height:1.5;margin:11px 0 8px;font-weight:650}.record p{font-size:11px;line-height:1.75;color:#586850;margin:7px 0}.context{font-size:10px!important;color:#8a9182!important}.protocolbox{background:#f5f7f0;border-radius:4px;padding:10px 12px;margin:12px 0;font-size:11px;line-height:1.7}.protocolbox small{display:block;font-size:8px;letter-spacing:1px;font-weight:700;color:#7b886f;margin-bottom:4px}.limitation{border-top:1px dashed #e0e5d8;margin-top:12px!important;padding-top:10px;color:#7b715a!important}.limitation b{font-size:9px;text-transform:uppercase;letter-spacing:.6px}.refs{display:flex;gap:6px;flex-wrap:wrap;margin-top:12px}.ref{font-size:9px;color:#637c56;border:1px solid #dce4d4;background:#fafcf7;border-radius:4px;padding:5px 7px}.ref:hover{background:#edf3e7}.empty{padding:35px 18px;text-align:center;color:#75816d;line-height:1.8}.empty h3,.empty h2{font:24px Georgia,serif;margin:0 0 10px}.empty p{font-size:12px}.empty button{color:var(--green);text-decoration:underline;font-size:12px}.sourcesview{padding:30px 0;max-width:1000px}.sourcesview h2{font:28px Georgia,serif}.sourcesview h3{font-size:14px;margin-top:25px}.sourcesview p{font-size:12px;line-height:1.8;max-width:850px;color:#65715d}.scopebox{padding:16px 20px;background:#eaf0e4;border-radius:7px;margin-bottom:25px}.sourcesgrid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:12px}.sourcecard{border:1px solid var(--line);background:var(--surface);color:var(--ink);border-radius:6px;padding:16px}.sourcecard h3{margin:8px 0;font-size:12px;line-height:1.5}.sourcecard p{font-size:11px;margin:5px 0}.sourcecard button,.sourcecard a{font-size:11px}.keytable{border-collapse:collapse;font-size:11px;width:100%;margin:20px 0 30px}.keytable td,.keytable th{text-align:left;padding:11px;border-bottom:1px solid var(--line);line-height:1.6}footer{border-top:1px solid var(--line);display:flex;justify-content:space-between;gap:16px;padding:21px 0 25px;color:#8a9280;font-size:9px}dialog{width:min(850px,94vw);max-height:88vh;padding:0;border:1px solid #ccd8c4;border-radius:12px;color:var(--ink);background:#fbfcf7;box-shadow:0 24px 100px #18322640}dialog::backdrop{background:#193b304f;backdrop-filter:blur(3px)}.readerhead{display:flex;justify-content:space-between;gap:20px;align-items:center;padding:22px 27px;border-bottom:1px solid var(--line)}.readerhead .eyebrow{margin:0 0 7px}.readerhead h2{font:23px Georgia,serif;margin:0}.iconbutton{border:1px solid var(--line);border-radius:50%;font-size:25px;width:32px;height:32px;line-height:20px;flex-shrink:0}.iconbutton:hover{background:#e6eddf}#reader-controls{padding:16px 27px;display:flex;gap:12px;align-items:center;flex-wrap:wrap}#reader-controls select{padding:7px;background:#fff;border:1px solid #ccd7c3;border-radius:4px;max-width:100%}#reader-controls label{font-size:11px}#reader-body{padding:0 27px 28px;font-size:12px;line-height:1.9;overflow-wrap:anywhere}#reader-body pre{font:12px/1.8 ui-sans-serif,system-ui;white-space:pre-wrap;color:#53634c;margin:15px 0}#reader-body a{overflow-wrap:anywhere}.source-status{font-size:10px;color:#728266}.skip{position:fixed;left:20px;top:-100px;background:var(--surface);color:var(--ink);padding:10px;z-index:5}.skip:focus{top:10px}.sr-only{position:absolute;width:1px;height:1px;padding:0;margin:-1px;overflow:hidden;clip:rect(0,0,0,0);white-space:nowrap;border:0}[hidden]{display:none!important}#load-error{padding:40px;color:#9a3c29}body:has(dialog[open]){overflow:hidden}@media(min-width:1450px){.layout{grid-template-columns:225px 380px minmax(0,1fr)}.record p{font-size:12px}.detail{padding-left:34px}.rowtop strong{font-size:14px}}@media(max-width:1100px){.layout{grid-template-columns:180px 260px minmax(0,1fr)}main{padding:0 3%}.filters{padding-right:15px}.detail{padding-left:20px}.legend{gap:8px}.overview{gap:16px}.record{padding:13px}.cataloglabels{font-size:7px}.rowtop strong{font-size:12px}.cataloghead,.compoundrow{padding-left:13px;padding-right:13px}}@media(max-width:900px){.layout{grid-template-columns:190px minmax(0,1fr)}.filters{grid-column:1;grid-row:1/3}.catalog{grid-column:2;border-right:0}.detail{grid-column:2;padding-left:20px;border-left:1px solid var(--line)}#results{max-height:300px;overflow:auto}.cataloglabels{font-size:8px}.rowtop strong{font-size:13px}.overview{flex-wrap:wrap}.legend{width:100%;margin-left:0;padding-top:3px;gap:18px}.intro h1{font-size:34px}.topbar{gap:20px}nav{margin-left:0;gap:15px}.sourcesgrid{grid-template-columns:1fr}}@media(max-width:600px){.topbar{height:auto;min-height:78px;padding:14px 5%;flex-wrap:wrap;gap:12px}.brand small{font-size:9px}.brand{font-size:10px}.brandmark{width:34px;height:36px;font-size:32px;padding-left:8px;line-height:26px}.private{font-size:9px;padding:5px 8px}nav{order:3;width:100%;height:28px;gap:22px}.navitem{font-size:11px}.intro{padding:25px 0 22px;display:block}.intro h1{font-size:32px}.intro p{font-size:12px}.snapshot{margin-top:18px;font-size:10px}.snapshot>span:not(.status-dot){display:inline;margin-right:10px}.snapshot strong{display:inline;margin-right:8px}.snapshot .textbutton{font-size:10px}.overview{gap:12px;font-size:9px;padding:12px 0}.overview strong{font-size:14px}.legend{font-size:9px;gap:11px}.searchbar{padding:18px 0 15px;gap:7px}.searchwrap{padding:0 10px;gap:6px;height:43px}.searchwrap input{font-size:11px}.searchwrap kbd{display:none}.subtle{font-size:10px;white-space:nowrap}.layout{display:block}.filters{padding:18px 0;display:grid;grid-template-columns:1fr 1fr;gap:12px}.filterheading{grid-column:1/-1;margin:0}.filterheading span{display:none}#pathways{grid-column:1/-1;display:flex;gap:6px;overflow:auto;padding:2px 0 7px}.pathbutton{width:auto;flex-shrink:0;white-space:nowrap;font-size:10px;padding:8px;background:#eef1e8;border:1px solid #dfe5d8}.pathbutton .count{margin-left:5px}.filtergroup{margin:0}.filter-note{grid-column:1/-1;margin:0;font-size:9px}.catalog{border:1px solid var(--line);border-radius:6px}.cataloghead{padding-top:17px}.cataloglabels{padding-left:13px}.compoundrow{min-height:75px;padding-top:13px;padding-bottom:13px}#results{max-height:260px}.detail{padding:25px 0;border:0}.detail h2{font-size:30px}.record{padding:16px}.record p{font-size:12px}.tabs{gap:25px}.tab{font-size:12px}.detailpath{font-size:9px}.gap{font-size:11px}.sourcecard h3{font-size:13px}footer{display:block;line-height:2}footer span{display:block}.readerhead{padding:18px}.readerhead h2{font-size:21px}#reader-controls{padding:13px 18px}#reader-body{padding:0 18px 22px}.keytable{font-size:10px}.sourcesview h2{font-size:26px}}

@media(min-width:601px){.record p{font-size:12px}.record h3{font-size:14px}.filtergroup label{font-size:12px}.filtergroup select{font-size:12px}.pathbutton{font-size:12px}.tab{font-size:12px}.target{font-size:13px}.protocolbox{font-size:12px}.gap{font-size:12px}}

.protocol-fields{margin:10px 0 0}.protocol-fields>div{display:grid;grid-template-columns:100px minmax(0,1fr);gap:12px;padding:8px 0;border-bottom:1px solid var(--line)}.protocol-fields dt{font-weight:600;font-size:11px}.protocol-fields dd{margin:0;overflow-wrap:anywhere}.protocol-verification{font-size:11px!important;color:var(--muted)!important}@media(max-width:600px){.protocol-fields>div{grid-template-columns:1fr;gap:3px}.protocol-fields dt{font-size:12px}.protocol-fields dd{font-size:14px}}
.home-compare{padding:25px 0 8px;border-top:1px solid var(--line)}.compare-head{padding:0 0 8px}.compare-head h2{font:25px/1.3 Georgia,serif;font-weight:400;margin:0 0 8px}.compare-grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:16px;padding:12px 0 8px}.compare-col{border:1px solid var(--line);border-radius:8px;background:var(--surface);padding:16px;min-width:0}.compare-col h3{font:22px Georgia,serif;font-weight:400;margin:12px 0}.compare-col h4{font-size:12px;margin:16px 0 6px}.compare-col label{display:block;font-size:12px;font-weight:600}.compare-col select{width:100%;min-height:44px;margin-top:6px;border:1px solid var(--line);border-radius:6px;background:var(--bg);color:var(--ink);padding:8px}.compare-classes{display:flex;flex-wrap:wrap;gap:8px}.compare-class{font-size:12px;color:var(--muted)}.compare-col ul{list-style:none;margin:0;padding:0}.compare-col li{padding:8px 0;border-bottom:1px solid var(--line)}@media(max-width:900px){.compare-grid{grid-template-columns:1fr}.compare-head h2{font-size:24px}}
.whats-new,.evidence-history{margin:8px 0 18px;padding-top:8px;border-top:1px solid var(--line)}.whats-new h3,.evidence-history h2,.evidence-history h3{font:20px Georgia,serif;font-weight:400;margin:0 0 6px}.whats-new .feed-note,.evidence-history .feed-note{font-size:11px;line-height:1.6;color:var(--muted);margin:0 0 8px}.whats-new ol,.evidence-history ol{list-style:none;margin:0;padding:0}.whats-new li,.evidence-history li{padding:10px 0;border-bottom:1px solid var(--line)}.whats-new li p{margin:6px 0 0;overflow-wrap:anywhere}.whats-new a{font-size:13px}.feed-meta{display:block;margin-top:4px;font-size:10px;color:var(--muted)}.history-when{font-size:10px;color:var(--muted);margin-right:6px}.feed-pending{display:inline-block;margin-left:6px;font-size:9px;font-weight:700;letter-spacing:.4px;text-transform:uppercase;color:#8e5c22;background:#fbefdf;border-radius:4px;padding:3px 6px;vertical-align:middle}
.trial-registry{margin:8px 0 18px;padding-top:8px;border-top:1px solid var(--line)}.trial-registry h3{font:20px Georgia,serif;font-weight:400;margin:0 0 6px}.trial-registry .feed-note,.trial-registry .feed-meta{font-size:11px;line-height:1.6;color:var(--muted)}.trial-registry ol{list-style:none;margin:8px 0 0;padding:0}.trial-registry li{padding:8px 0;border-bottom:1px solid var(--line)}.trial-registry a{overflow-wrap:anywhere}

.home-welcome{padding:38px 0 30px;max-width:760px}.home-welcome h2{font:42px/1.15 Georgia,serif;font-weight:400;letter-spacing:-1px;margin:0 0 16px}.home-welcome>p{font-size:15px;line-height:1.8;color:var(--muted);max-width:650px}.home-actions{display:flex;gap:12px;flex-wrap:wrap;margin:24px 0 16px}.home-actions button{min-height:48px;padding:14px 20px;border-radius:8px;font-size:14px;display:flex;align-items:center;justify-content:space-between;gap:25px}.home-primary{background:var(--green);color:white}.home-secondary{background:var(--surface);color:var(--green);border:1px solid var(--line)}.home-welcome .home-note{font-size:12px;line-height:1.7}.home-paths,.home-evidence-guide{padding:25px 0;border-top:1px solid var(--line)}.home-section-heading{display:flex;justify-content:space-between;align-items:center;gap:12px;margin-bottom:18px;flex-wrap:wrap}.home-section-heading h2{font:25px/1.3 Georgia,serif;margin:0}.home-section-heading>span{font-size:12px;color:var(--muted)}.home-path-grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:12px}.home-path{padding:20px;min-height:100px;background:var(--surface);border:1px solid var(--line);border-radius:8px;text-align:left;display:flex;flex-direction:column;gap:12px;justify-content:space-between}.home-path:hover{background:var(--pale)}.home-path strong{font-size:15px;font-weight:600}.home-path>span{font-size:12px;color:var(--muted)}.home-path>span>span{float:right;color:var(--green)}.home-evidence-grid{display:grid;grid-template-columns:repeat(5,minmax(0,1fr));gap:18px}.home-evidence-grid article{min-width:0}.home-evidence-grid .badge{font-size:11px}.home-evidence-grid p{font-size:12px;line-height:1.8;color:var(--muted)}.choose-compound{padding:55px 20px}.choose-compound p{font-size:14px;line-height:1.8}@media(max-width:900px){.home-path-grid{grid-template-columns:repeat(2,minmax(0,1fr))}.home-evidence-grid{grid-template-columns:repeat(2,minmax(0,1fr))}.home-welcome{padding:28px 0}.home-welcome h2{font-size:34px}}@media(max-width:600px){.home-welcome h2{font-size:32px}.home-welcome>p{font-size:14px}.home-actions{display:grid;grid-template-columns:1fr}.home-actions button{width:100%;font-size:15px;min-height:50px}.home-path-grid{grid-template-columns:1fr}.home-path{padding:16px;min-height:90px}.home-evidence-grid{grid-template-columns:1fr;gap:12px}.home-evidence-grid article{padding:8px 0}.home-evidence-grid p{font-size:13px;margin:8px 0}.home-section-heading .textbutton{min-height:44px;font-size:12px}}

.contact-link{display:inline-flex;align-items:center;min-height:44px;text-decoration:underline;text-underline-offset:3px;white-space:nowrap}.topbar nav:has(.contact-link){gap:16px;overflow-x:auto}.topbar nav .navitem{flex-shrink:0;white-space:nowrap}

/* Align anchor and button navigation items on one baseline across all Atlas pages. */
.topbar nav .navitem{display:inline-flex;align-items:center;justify-content:center;text-decoration:none;line-height:1.2;vertical-align:middle;flex-shrink:0;white-space:nowrap}
.topbar nav{align-items:stretch;min-width:0}
.topbar nav .navitem:hover{text-decoration:none;color:var(--green)}
@media(max-width:900px){.topbar nav{overflow:visible;flex-wrap:wrap;height:auto;gap:4px 16px}.topbar nav .navitem{height:44px;min-height:44px}}
body[data-view="explorer"] .intro,body[data-view="review"] .intro,body[data-view="sources"] .intro,body[data-view="explorer"] #overview,body[data-view="review"] #overview,body[data-view="sources"] #overview,body[data-view="explorer"] #general-research,body[data-view="review"] #general-research,body[data-view="sources"] #general-research{display:none}
.home-general{padding:8px 0 28px}.home-general #lab-testing-guide{margin:0;border:1px solid var(--line);border-radius:8px;background:var(--surface);padding:4px 16px 8px}.home-general #lab-testing-guide summary{min-height:44px;display:flex;align-items:center;cursor:pointer;font-weight:650}.owner-ops{margin-left:auto;display:inline-flex;align-items:center;min-height:44px;padding:0 8px;color:var(--muted);font-size:11px;letter-spacing:.04em;text-decoration:none}.topbar:has(.owner-ops) .private{margin-left:8px}
.source-review{margin:6px 0 0;color:var(--muted);font-size:12px}
.topbar-tools{display:flex;align-items:center;gap:8px;margin-left:auto}.topbar:has(.topbar-tools) .owner-ops,.topbar:has(.topbar-tools) .private{margin-left:0}
@media(max-width:600px){nav{height:auto}.topbar{display:grid;grid-template-columns:minmax(0,1fr) auto;grid-template-areas:"brand tools" "nav nav";height:auto;row-gap:4px;align-items:center}.topbar .brand{grid-area:brand}.topbar nav{grid-area:nav;order:0;width:100%;height:auto}.topbar-tools{grid-area:tools;margin-left:0}.topbar .owner-ops{order:0}}
.count-badge{display:inline-block;min-width:18px;margin-left:6px;padding:1px 6px;border-radius:999px;background:var(--green);color:var(--bg);font-size:11px;font-weight:700;line-height:16px;text-align:center;vertical-align:middle}.count-badge[hidden]{display:none}.bulk-bar{display:flex;flex-wrap:wrap;align-items:center;gap:8px 12px;margin:8px 0 12px;padding:8px 10px;border:1px solid var(--line);border-radius:8px}.bulk-bar[hidden]{display:none}.bulk-bar label,.claim-card label.bulk-select{margin:0;display:inline-flex;align-items:center;gap:8px;min-height:32px;cursor:pointer}.bulk-bar input,.bulk-select input{width:18px;height:18px;margin:0}.bulk-count{color:var(--muted);font-size:13px;margin-right:auto}
.glossary{margin:8px 0 22px;padding-top:8px;border-top:1px solid var(--line)}.glossary summary{min-height:44px;display:list-item;padding:10px 0;cursor:pointer;color:var(--green);font-weight:600}.glossary h3{font:17px Georgia,serif;font-weight:400;margin:18px 0 6px}.glossary dl{display:grid;grid-template-columns:repeat(auto-fit,minmax(min(100%,300px),1fr));gap:4px 24px;margin:0}.glossary dl>div{padding:6px 0;border-bottom:1px solid var(--line)}.glossary dt{font-weight:650}.glossary dd{margin:2px 0 0;color:var(--muted);line-height:1.5}
.searchwrap input{min-height:40px}
@media print{body{background:#fff!important;color:#000!important}body *:not(:has(#detail)):not(#detail):not(#detail *),#detail .detailtools,#detail .detail-reading-nav{display:none!important}.layout,#detail{display:block!important;width:auto!important;max-width:none!important;margin:0!important;padding:0!important;border:0!important;box-shadow:none!important;background:#fff!important;color:#000!important}#detail *{color:#000!important;background:transparent!important}#detail a[href^="http"]::after{content:" (" attr(href) ")";font-size:9pt;word-break:break-all}.record{break-inside:avoid;border:1px solid #999!important}}
.tl-filters{display:flex;flex-wrap:wrap;gap:6px;margin:4px 0 10px}.tl-filters button{min-height:32px;padding:4px 12px;border:1px solid var(--line);border-radius:999px;background:transparent;color:var(--muted);font:inherit;font-size:13px;cursor:pointer}.tl-filters button[aria-pressed="true"]{border-color:var(--green);color:var(--ink)}.tl-list{list-style:none;margin:0;padding:0}.tl-list>li{display:grid;grid-template-columns:92px minmax(0,1fr);gap:10px;padding:8px 0;border-bottom:1px solid var(--line)}.tl-list>li p{margin:4px 0}.tl-kind{font-size:12px;color:var(--muted);text-transform:uppercase;letter-spacing:.04em}.tl-older summary{min-height:44px;display:list-item;padding:10px 0;cursor:pointer;color:var(--green)}@media(max-width:600px){.tl-list>li{grid-template-columns:1fr;gap:2px}}
main{min-height:100vh}#home-view:empty{min-height:100vh}
.review-loading{visibility:hidden}
.timeline[data-show="new"] :is(li,.tl-dot)[data-kind]:not([data-kind="new"]),.timeline[data-show="change"] :is(li,.tl-dot)[data-kind]:not([data-kind="change"]),.timeline[data-show="trial"] :is(li,.tl-dot)[data-kind]:not([data-kind="trial"]){display:none}.tl-strip{position:relative;margin:6px 8px 12px;min-height:47px}.tl-axis{position:absolute;left:0;right:0;bottom:18px;border-top:1px solid var(--line)}.tl-tick{position:absolute;bottom:0;transform:translateX(-50%);font-size:10px;line-height:14px;color:var(--muted);white-space:nowrap}.tl-tick::before{content:"";position:absolute;left:50%;top:-5px;height:4px;border-left:1px solid var(--line)}.tl-dot{position:absolute;width:12px;height:12px;margin-left:-6px;border-radius:50%;border:2px solid var(--bg);box-sizing:content-box}.tl-dot::after{content:"";position:absolute;inset:-6px}.tl-dot[data-kind="new"],.tl-key[data-kind="new"]{background:var(--human)}.tl-dot[data-kind="change"],.tl-key[data-kind="change"]{background:var(--anec)}.tl-dot[data-kind="trial"],.tl-key[data-kind="trial"]{background:var(--theory)}.tl-dot:hover,.tl-dot:focus-visible{outline:2px solid var(--ink);outline-offset:1px;z-index:1}.tl-key{display:inline-block;width:9px;height:9px;border-radius:50%;margin-right:6px;vertical-align:0}.tl-flash{animation:tl-flash 1.6s ease-out}@keyframes tl-flash{from{background:var(--pale)}to{background:transparent}}@media(prefers-reduced-motion:reduce){.tl-flash{animation:none;outline:2px solid var(--green)}}.new-badge{display:inline-block;margin-left:6px;padding:1px 6px;border-radius:999px;background:var(--green);color:var(--bg);font:700 10px/16px system-ui,sans-serif;letter-spacing:.03em;vertical-align:middle;text-transform:uppercase}.visit-banner{display:flex;flex-wrap:wrap;align-items:center;gap:6px 12px;margin:10px 0;padding:10px 12px;border:1px solid var(--line);border-radius:8px;background:var(--surface);font-size:13px}.visit-banner[hidden]{display:none}.visit-banner p{margin:0;flex:1 1 220px}.visit-banner button{min-height:36px;padding:4px 12px;border:1px solid var(--line);border-radius:999px;background:transparent;color:var(--ink);font:inherit;cursor:pointer}.visit-banner button[aria-pressed="true"]{border-color:var(--green)}
.undo-tray{position:fixed;left:50%;bottom:16px;transform:translateX(-50%);z-index:20;display:grid;gap:8px;width:min(560px,calc(100% - 32px))}.undo-note{display:flex;align-items:center;gap:10px;padding:10px 12px;border-radius:10px;background:var(--ink);color:var(--bg);box-shadow:0 6px 24px #0005;font-size:14px}.undo-note span:first-child{flex:1;min-width:0;overflow:hidden;text-overflow:ellipsis;white-space:nowrap}.undo-clock{font-size:12px;opacity:.75;white-space:nowrap}.undo-note button{min-height:40px;padding:6px 14px;border:1px solid currentColor;border-radius:8px;background:transparent;color:inherit;font:inherit;font-weight:700;cursor:pointer}
.compare-pickers{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:12px;margin:8px 0 14px}.compare-pick{font-size:12px;font-weight:600}.compare-pick select{width:100%;min-height:44px;margin-top:6px;border:1px solid var(--line);border-radius:6px;background:var(--bg);color:var(--ink);padding:8px}.compare-table{border:1px solid var(--line);border-radius:8px;background:var(--surface);overflow-x:auto}.compare-row{display:grid;grid-template-columns:minmax(118px,.8fr) repeat(var(--compare-cols),minmax(150px,1fr));border-top:1px solid var(--line)}.compare-row:first-child{border-top:0}.compare-label{position:sticky;left:0;z-index:1;padding:10px 12px;font-size:12px;font-weight:650;color:var(--muted);background:var(--surface)}.compare-note{display:block;font-weight:400;font-size:11px;opacity:.8}.compare-cell{padding:10px 12px;font-size:13px;line-height:1.45;border-left:1px solid var(--line);min-width:0;overflow-wrap:anywhere}.compare-differs{background:linear-gradient(var(--pale),var(--pale));background-size:3px 100%;background-repeat:no-repeat}.compare-same .compare-cell{color:var(--muted)}.compare-name a{font:18px/1.25 Georgia,serif;color:var(--ink)}.compare-name span{display:block;font-size:11px;color:var(--muted);margin-top:2px}.compare-bars{display:grid;gap:4px}.compare-bar{display:grid;grid-template-columns:14px 1fr 26px;align-items:center;gap:6px;font-size:11px}.compare-bar-label{color:var(--muted);font-weight:700}.compare-bar-track{height:8px;border-radius:4px;background:var(--pale);overflow:hidden}.compare-bar-fill{display:block;height:100%;border-radius:4px;transition:width .5s ease}.compare-bar-fill.tier-H{background:var(--human)}.compare-bar-fill.tier-P{background:var(--pre)}.compare-bar-fill.tier-T{background:var(--theory)}.compare-bar-fill.tier-A{background:var(--anec)}.compare-bar-fill.tier-U{background:var(--unknown)}.compare-bar-n{text-align:right;font-variant-numeric:tabular-nums}.compare-chip{display:inline-block;margin:0 4px 4px 0;padding:1px 8px;border:1px solid var(--line);border-radius:999px;font-size:12px}.compare-only{border-color:var(--green);color:var(--green);font-weight:650}.compare-fresh{animation:compare-in .45s ease-out}.compare-fresh .compare-bar-fill{animation:compare-grow .7s ease-out}@keyframes compare-in{from{opacity:0;transform:translateY(6px)}to{opacity:1;transform:none}}@keyframes compare-grow{from{width:0}}@media(prefers-reduced-motion:reduce){.compare-fresh,.compare-fresh .compare-bar-fill{animation:none}}@media(max-width:600px){.compare-pickers{grid-template-columns:1fr}.compare-row{grid-template-columns:96px repeat(var(--compare-cols),minmax(136px,1fr))}}
.compound-preview{position:fixed;z-index:30;width:min(300px,calc(100vw - 16px));padding:12px 14px;border:1px solid var(--line);border-radius:10px;background:var(--surface);color:var(--ink);box-shadow:0 10px 30px #0004;pointer-events:none;font-size:13px;animation:compare-in .15s ease-out}.compound-preview[hidden]{display:none}.preview-top{display:flex;align-items:center;gap:6px;font-size:15px}.preview-meta{color:var(--muted);font-size:12px;margin:2px 0 8px}.preview-routes{margin:8px 0 2px}.preview-latest{font-size:12px;line-height:1.45;margin-top:6px;padding-top:6px;border-top:1px solid var(--line)}.preview-hint{margin-top:6px;font-size:11px;color:var(--muted)}@media(prefers-reduced-motion:reduce){.compound-preview{animation:none}}
.review-live{display:flex;flex-wrap:wrap;align-items:center;gap:8px 12px;margin:8px 0 12px;padding:10px 12px;border:1px solid var(--green);border-radius:8px;background:var(--surface);font-size:13px}.review-live[hidden]{display:none}.review-live span{flex:1 1 220px}.review-live button{min-height:40px;padding:6px 14px;border:1px solid var(--line);border-radius:8px;background:transparent;color:var(--ink);font:inherit;font-weight:650;cursor:pointer}
.compare-cell ul{list-style:none;margin:0;padding:0}.compare-cell li{padding:0 0 8px}.compare-cell li:last-child{padding:0}.compare-cell p{margin:0 0 6px}
.ev-chart{margin:10px 0 12px}.ev-chart:empty{display:none}.ev-chart-head{display:flex;flex-wrap:wrap;align-items:baseline;gap:4px 12px;margin-bottom:6px}.ev-chart-total{font-weight:650;font-size:13px}.ev-bar{display:flex;height:14px;border-radius:7px;overflow:hidden;background:var(--pale);gap:2px}.ev-seg{flex:0 1 0;min-width:0;padding:0;border:0;cursor:pointer;transition:flex-grow .35s ease,opacity .2s}.ev-seg.ev-dim{opacity:.25}.ev-seg.tier-H,.ev-swatch.tier-H{background:var(--human)}.ev-seg.tier-P,.ev-swatch.tier-P{background:var(--pre)}.ev-seg.tier-T,.ev-swatch.tier-T{background:var(--theory)}.ev-seg.tier-A,.ev-swatch.tier-A{background:var(--anec)}.ev-seg.tier-U,.ev-swatch.tier-U{background:var(--unknown)}.ev-legend{display:flex;flex-wrap:wrap;gap:6px;margin-top:8px}.ev-key{display:inline-flex;align-items:center;gap:6px;min-height:36px;padding:4px 10px;border:1px solid var(--line);border-radius:999px;background:transparent;color:var(--ink);font:inherit;font-size:12px;cursor:pointer}.ev-key[aria-pressed="true"]{border-color:var(--green);box-shadow:inset 0 0 0 1px var(--green)}.ev-key:disabled{opacity:.45;cursor:default}.ev-n{color:var(--muted);font-variant-numeric:tabular-nums}.ev-swatch{width:10px;height:10px;border-radius:50%}@media(max-width:600px){.ev-name{font-size:11px}}@media(prefers-reduced-motion:reduce){.ev-seg{transition:none}}.ref[aria-expanded="true"]{border-color:var(--green);background:var(--pale)}.cite-panel{margin:8px 0 4px;padding:10px 12px;border:1px solid var(--line);border-left:3px solid var(--green);border-radius:8px;background:var(--surface);font-size:13px;animation:compare-in .2s ease-out}.cite-panel[hidden]{display:none}.cite-top{display:flex;align-items:flex-start;gap:8px}.cite-top strong{flex:1;line-height:1.4}.cite-close{min-width:36px;min-height:36px;border:1px solid var(--line);border-radius:8px;background:transparent;color:var(--ink);font-size:18px;line-height:1;cursor:pointer}.cite-facts{display:grid;grid-template-columns:repeat(auto-fit,minmax(140px,1fr));gap:6px 14px;margin:8px 0}.cite-facts dt{font-size:11px;color:var(--muted);text-transform:uppercase;letter-spacing:.04em}.cite-facts dd{margin:2px 0 0}.cite-note{margin:6px 0;color:var(--muted);line-height:1.5}.cite-links{display:flex;flex-wrap:wrap;gap:6px 16px;align-items:center;margin:6px 0}@media(prefers-reduced-motion:reduce){.cite-panel{animation:none}}
.phase-track-wrap{margin:10px 0 12px}.phase-title{font-size:12px;margin:0 0 6px;color:var(--muted);text-transform:uppercase;letter-spacing:.05em}.phase-track{display:grid;grid-template-columns:repeat(6,minmax(0,1fr));gap:6px;list-style:none;margin:0;padding:0;counter-reset:none}.phase-step{position:relative;display:grid;gap:3px;align-content:start;padding:8px;border:1px solid var(--line);border-radius:8px;background:var(--surface);font-size:12px;min-width:0}.phase-step:not(:last-child)::after{content:"›";position:absolute;right:-6px;top:50%;transform:translate(50%,-50%);color:var(--muted);font-size:14px;z-index:1}.phase-name{font-weight:650}.phase-n{font:20px/1 Georgia,serif}.phase-meter{display:block;height:5px;border-radius:3px;background:var(--pale);overflow:hidden}.phase-meter span{display:block;height:100%;background:var(--green)}.phase-detail{color:var(--muted);font-size:11px;line-height:1.35}.phase-empty{border-style:dashed;background:transparent}.phase-empty .phase-n,.phase-empty .phase-name{color:var(--muted)}.phase-fda{border-style:dashed}@media(max-width:700px){.phase-track{grid-template-columns:repeat(3,minmax(0,1fr))}.phase-step:nth-child(3n)::after{display:none}}
.palette{width:min(620px,calc(100vw - 24px));max-height:min(560px,calc(100vh - 80px));margin:10vh auto auto;padding:0;border:1px solid var(--line);border-radius:12px;background:var(--surface);color:var(--ink);box-shadow:0 20px 60px #0006}.palette::backdrop{background:#0008}.palette-box{display:flex;flex-direction:column;max-height:inherit}.palette input{margin:0;padding:16px;border:0;border-bottom:1px solid var(--line);background:transparent;color:var(--ink);font:inherit;font-size:16px;outline:none}.palette ul{list-style:none;margin:0;padding:6px;overflow-y:auto}.palette li{display:grid;grid-template-columns:76px 1fr;gap:0 10px;padding:8px 10px;border-radius:8px;cursor:pointer}.palette li[aria-selected="true"]{background:var(--pale)}.palette-group{grid-row:span 2;align-self:center;font-size:10px;font-weight:700;letter-spacing:.06em;text-transform:uppercase;color:var(--muted)}.palette-label{font-weight:650}.palette-sub{font-size:12px;color:var(--muted);white-space:nowrap;overflow:hidden;text-overflow:ellipsis}.palette-none{color:var(--muted);cursor:default}.palette-help{margin:0;padding:8px 14px;border-top:1px solid var(--line);font-size:11px;color:var(--muted)}.palette-open{display:inline-flex;align-items:center;gap:8px}.palette-open kbd{font:600 10px/1 system-ui,sans-serif;padding:3px 5px;border:1px solid var(--line);border-radius:4px;color:var(--muted)}@media(max-width:600px){.palette-open kbd{display:none}.palette{margin-top:12px}}
.home-compare{min-width:0;max-width:100%}.compare-table{position:relative;max-width:100%}
.record-group{margin:14px 0;border-top:1px solid var(--line)}.record-group>summary{display:flex;align-items:center;gap:10px;min-height:44px;padding:8px 0;cursor:pointer;font-size:13px}.record-group>summary .record-group-count{color:var(--muted)}.record-group-tools{display:flex;flex-wrap:wrap;align-items:center;gap:4px 16px;margin:4px 0}.record-group-tools .textbutton{min-height:44px}
@media print{.record-group>summary{list-style:none}.record-group-tools{display:none}}
.record-group-tools>span{color:var(--muted);font-size:12px;margin-left:auto}


/* Shared research launchpad: the homepage begins with the research task. */
body[data-view="home"] .intro{padding:24px 0 18px}
body[data-view="home"] .intro h1{font-size:28px;letter-spacing:-.6px}
body[data-view="home"] .intro .eyebrow,body[data-view="home"] .intro .edition{display:none}
body[data-view="home"] .intro p{font-size:12px;margin-top:7px}
.research-launchpad{display:grid;grid-template-columns:minmax(0,1.5fr) minmax(280px,1fr);gap:40px;margin:28px 0 36px;padding:40px;border:1px solid #385d88;border-radius:20px;background:radial-gradient(ellipse at 0 0,#244a72 0,transparent 70%),#14273e;color:#f4f8ff;box-shadow:0 18px 45px #0b1b3420}
.research-launchpad .home-welcome{max-width:none;padding:0}
.research-launchpad .eyebrow{color:#a8cffc}
.research-launchpad h2{font-size:clamp(34px,4vw,54px);letter-spacing:-1.5px;line-height:1.08;margin:0 0 18px;color:#f4f8ff}
.research-launchpad .home-welcome>p{color:#c2d3e7;max-width:490px;line-height:1.7;margin:12px 0}
.home-search-form{margin-top:24px}
.home-search-form>label{display:block;font-size:12px;font-weight:600;color:#d9e7f8;margin-bottom:9px}
.home-search-field{display:flex;gap:8px;padding:7px;background:#f6f9fe;border:1px solid #bacde5;border-radius:12px}
.home-search-field input{min-width:0;flex:1;width:100%;padding:10px;border:0;border-radius:6px;background:#f6f9fe;color:#162d47;font-size:16px;color-scheme:light}
:root .home-search-field input::placeholder{color:#52677d}
.home-search-field button{flex-shrink:0;background:#285e99;color:#fff;padding:12px 16px;border-radius:7px;font-weight:650;min-height:48px}
.home-search-field button span{margin-left:12px}
.home-starters{display:flex;gap:8px;align-items:center;flex-wrap:wrap;margin:14px 0 20px;font-size:12px;color:#c2d3e7}
.home-starters button{border:1px solid #587494;border-radius:20px;padding:8px 12px;color:#e5effb;min-height:36px;background:#203c59}
.research-launchpad .home-welcome .home-note{font-size:12px;margin:0;color:#b9cce3}
.launch-routes{align-self:center;min-width:0}
.launch-routes>button,.launch-routes>a{display:flex;align-items:center;gap:16px;width:100%;text-decoration:none;text-align:left;color:#f4f8ff;border:1px solid #4a6584;background:#ffffff08;padding:18px;border-radius:10px;margin:10px 0;min-height:82px}
.launch-routes strong{display:block;font-size:15px;font-weight:650}.launch-routes small{display:block;color:#bed0e5;font-size:12px;margin-top:6px;line-height:1.5}
.launch-routes>button>span:last-child,.launch-routes>a>span:last-child{margin-left:auto;color:#b7d6fc}
.launch-number{font:12px ui-monospace,monospace;color:#9ebee2}
.launch-routes>button:hover,.launch-routes>a:hover,.home-starters button:hover{background:#345579;border-color:#a8cffc}
.research-launchpad :focus-visible{outline:3px solid #f3cf76;outline-offset:3px}
.launch-footnote{position:relative;padding-left:16px;color:#b9cce3;font-size:11px;margin-top:20px;line-height:1.6}
.launch-footnote .status-dot{top:6px;background:#7cd4bf}
#compare-library{scroll-margin-top:20px}
@media(max-width:1000px){.research-launchpad{gap:24px;padding:28px;grid-template-columns:minmax(0,1.3fr) minmax(250px,1fr)}.home-search-field{flex-wrap:wrap}.home-search-field button{width:100%}}
@media(max-width:700px){.research-launchpad{grid-template-columns:1fr;padding:24px 20px;gap:26px;border-radius:14px;margin:20px 0 28px}.research-launchpad h2{font-size:38px}.research-launchpad .home-welcome>p{font-size:14px}.launch-routes>button,.launch-routes>a{min-height:72px;padding:14px}.home-search-field input{min-height:46px}.home-starters button{min-height:44px}.research-launchpad .home-welcome .home-note{font-size:12px}body[data-view="home"] .intro h1{font-size:26px}}

/* Evidence-first compound workspace, shared by both editions. */
.detail-map{display:flex;align-self:auto;flex-wrap:wrap;gap:8px;position:sticky;top:0;z-index:4;margin:22px 0 20px;padding:12px;background:var(--bar,var(--surface));border:1px solid var(--line);border-radius:12px;box-shadow:0 8px 20px #101b2c12}
.detail-map>a,.detail-map>button{display:flex;align-items:center;gap:8px;color:var(--ink);font-size:12px;font-weight:650;text-decoration:none;padding:10px 12px;min-height:44px;border-radius:8px;background:var(--surface)}
.detail-map>a{background:var(--primary,var(--green));color:var(--on-primary,#fff)}.detail-map span{font-size:11px;opacity:.8}
.research-drawer{border:1px solid var(--line);border-radius:12px;background:var(--surface);margin:20px 0;scroll-margin-top:85px;overflow:hidden}
.research-drawer>summary{padding:20px;cursor:pointer;font-size:18px;font-weight:650;min-height:72px}.research-drawer>summary small{display:block;font-size:12px;font-weight:400;color:var(--muted);margin:7px 0 0 20px}
.research-drawer>.timeline,.research-drawer>.trial-registry{border:0;padding:0 20px 20px;margin:0}
#record-panel{scroll-margin-top:85px}
@media(max-width:600px){.detail-map{gap:6px;padding:8px}.detail-map>a,.detail-map>button{flex:1;justify-content:center;padding:9px 7px;font-size:11px}.research-drawer>summary{font-size:17px;padding:16px}}
@media print{.detail-map{display:none}.research-drawer{break-inside:auto}.research-drawer>summary{font-size:16px}.research-drawer::details-content{content-visibility:visible}}

/* The unselected library is a browsable directory, rather than an empty reader. */
.row-target,.row-evidence{display:none}
.layout.directory-mode{grid-template-columns:210px minmax(0,1fr)}
.directory-mode .detail{display:none}.directory-mode .catalog{display:block;min-width:0;border-right:0;padding:0 0 24px 24px}
.directory-mode .cataloglabels{display:none}.directory-mode .cataloghead{padding-left:0}
.directory-mode #results{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:16px;max-height:none;overflow:visible}
.directory-mode .compoundrow{display:flex;flex-direction:column;gap:10px;align-items:stretch;text-align:left;border:1px solid var(--line);border-radius:14px;background:var(--surface);padding:22px;min-height:220px;transition:border-color .15s,box-shadow .15s}
.directory-mode .compoundrow:hover{border-color:var(--green);box-shadow:0 8px 25px #182c4415}
.directory-mode .rowtop strong{font-size:19px;line-height:1.35;letter-spacing:-.3px}.directory-mode .rowpath{font-size:11px;letter-spacing:.4px}
.directory-mode .row-target{display:block;font-size:13px;line-height:1.6;color:var(--ink)}
.directory-mode .row-evidence{display:flex;flex-wrap:wrap;gap:7px 12px;margin-top:auto;align-items:center}.directory-mode .row-evidence>span{display:inline-flex;align-items:center;gap:5px;font-size:11px;color:var(--ink)}
.directory-mode .row-evidence .badge{font-size:9px;padding:4px 6px;white-space:normal}
.directory-mode .rowmeta{border-top:1px solid var(--line);padding-top:12px;font-size:11px;color:var(--muted)}
@media(min-width:1500px){.directory-mode #results{grid-template-columns:repeat(3,minmax(0,1fr))}}
@media(max-width:900px){.layout.directory-mode{display:block}.directory-mode .catalog{padding:0;border:0}.directory-mode #results{grid-template-columns:repeat(2,minmax(0,1fr))}.directory-mode .compoundrow{min-height:215px;padding:18px}}
@media(max-width:600px){.directory-mode #results{grid-template-columns:minmax(0,1fr);gap:12px}.directory-mode .compoundrow{min-height:0;padding:20px}.directory-mode .rowtop strong{font-size:21px}.directory-mode .row-evidence{margin-top:6px}}

/* Select compounds in place, then compare without losing the browsing context. */
.compare-pick-action{display:none}.compound-choice{min-width:0}
.directory-mode .compound-choice{display:flex;flex-direction:column;background:var(--surface);border:1px solid var(--line);border-radius:14px;overflow:hidden}
.directory-mode .compound-choice .compoundrow{border:0;border-radius:0;flex:1;box-shadow:none}
.directory-mode .compare-pick-action{display:block;text-align:left;min-height:46px;padding:12px 22px;background:var(--panel,var(--pale));color:var(--green);font-size:12px;font-weight:650;border-top:1px solid var(--line)}
.directory-mode .compare-pick-action[aria-pressed="true"]{background:var(--primary);color:var(--on-primary)}
.compare-tray[hidden]{display:none}.compare-tray{position:fixed;z-index:15;bottom:16px;left:50%;transform:translateX(-50%);width:min(1040px,calc(100% - 32px));display:grid;grid-template-columns:auto minmax(0,1fr) auto auto;align-items:center;gap:10px 18px;background:var(--bar,var(--surface));color:var(--ink);border:1px solid var(--green);padding:16px 20px;border-radius:16px;box-shadow:0 12px 60px #07152655}
.tray-heading strong,.tray-heading>span{display:block}.tray-heading strong{font-size:14px}.tray-heading>span{font-size:11px;color:var(--muted);margin-top:5px}.tray-picks{display:flex;flex-wrap:wrap;gap:7px}.tray-picks button{border:1px solid var(--line);border-radius:20px;background:var(--surface);color:var(--ink);padding:8px 12px;min-height:44px;font-size:12px}.tray-picks button span{padding-left:7px}
.tray-open{background:var(--primary);color:var(--on-primary);padding:12px 16px;min-height:44px;border-radius:8px;font-size:13px;font-weight:650}.tray-open:disabled{opacity:.55;cursor:not-allowed}.tray-clear{color:var(--green);font-size:12px;min-height:44px;padding:8px}.tray-message{grid-column:2/-1;font-size:11px;color:var(--muted);margin:0;order:5}.has-compare-tray{padding-bottom:160px}
@media(max-width:700px){.compare-tray{bottom:8px;width:calc(100% - 16px);padding:12px;gap:8px;grid-template-columns:1fr auto}.tray-heading{grid-column:1}.tray-picks{grid-column:1/-1;grid-row:2}.tray-open{grid-column:1;grid-row:3}.tray-clear{grid-column:2;grid-row:3}.tray-message{grid-column:1/-1}.has-compare-tray{padding-bottom:260px}#record-panel,.research-drawer{scroll-margin-top:150px}}
@media print{.compare-tray,.compare-pick-action{display:none!important}.has-compare-tray{padding-bottom:0}}

/* Searchable citation workspace; source labels retain their original scope. */
.source-workspace{max-width:none}.source-hero{padding:28px 0}.source-hero h2{font:46px/1.12 Georgia,serif;letter-spacing:-1px;margin:0 0 16px}.source-hero>p{max-width:720px;line-height:1.8;font-size:14px;color:var(--muted)}
.source-controls{display:grid;grid-template-columns:minmax(220px,2fr) repeat(3,minmax(130px,1fr));gap:14px;padding:20px;border:1px solid var(--line);background:var(--panel,var(--pale));border-radius:14px}
.source-controls label{display:grid;gap:8px;font-size:12px;font-weight:650;min-width:0}.source-controls input,.source-controls select{width:100%;min-width:0;min-height:48px;border:1px solid var(--line);border-radius:8px;padding:12px;background:var(--surface);color:var(--ink);font-size:14px}
.source-results-heading{display:flex;justify-content:space-between;align-items:center;gap:12px;margin:16px 0}.source-results-heading p{margin:0;font-size:13px}.source-results-heading button{min-height:44px}
.source-method{border:1px solid var(--line);border-radius:10px;margin:0 0 24px;padding:0 20px;background:var(--surface)}.source-method>summary{padding:18px 0;cursor:pointer;font-size:13px;font-weight:650}.source-method .scopebox{margin-top:4px}
.source-workspace .sourcesgrid{grid-template-columns:repeat(2,minmax(0,1fr));gap:18px}.source-workspace .sourcecard{display:flex;flex-direction:column;border-radius:14px;padding:24px;min-width:0}.source-workspace .sourcecard h3{font-size:18px;line-height:1.5;margin:14px 0 10px}.source-workspace .source-kind{font-size:12px;color:var(--muted)}.source-workspace .source-usage{font-size:11px;margin:10px 0}
.source-compounds{display:flex;flex-wrap:wrap;gap:7px}.source-compounds a{display:inline-flex;align-items:center;gap:8px;border:1px solid var(--line);border-radius:18px;padding:8px 11px;text-decoration:none;color:var(--green);font-size:11px;min-height:40px}.source-compounds span{color:var(--muted)}
.source-note{border-top:1px solid var(--line);margin:16px 0 10px;padding-top:14px}.source-note summary{font-size:12px;cursor:pointer}.source-workspace .source-note p{font-size:12px;line-height:1.75}.source-workspace .sourcecard>.textbutton{align-self:flex-start;min-height:44px;margin-top:auto}
@media(max-width:1000px){.source-controls{grid-template-columns:repeat(2,minmax(0,1fr))}}
@media(max-width:600px){.source-hero h2{font-size:36px}.source-controls{grid-template-columns:minmax(0,1fr);padding:16px}.source-controls input,.source-controls select{font-size:16px}.source-workspace .sourcesgrid{grid-template-columns:minmax(0,1fr)}.source-workspace .sourcecard{padding:20px}.source-method{padding:0 14px}.source-compounds a{min-height:44px}}

.evidence-lenses{padding:24px 0 32px}.lens-grid{display:grid;grid-template-columns:repeat(5,minmax(0,1fr));gap:12px}.lens-grid>button{display:flex;flex-direction:column;align-items:flex-start;text-align:left;gap:12px;padding:20px;border:1px solid var(--line);border-radius:14px;background:var(--surface);color:var(--ink);min-height:190px}.lens-grid strong{font:36px Georgia,serif}.lens-grid>button>span:not(.badge){font-size:11px;color:var(--muted);line-height:1.6}.lens-grid small{margin-top:auto;font-size:11px;color:var(--green)}.lens-grid>button:hover{background:var(--pale);border-color:var(--green)}@media(max-width:1000px){.lens-grid{grid-template-columns:repeat(3,minmax(0,1fr))}}@media(max-width:600px){.lens-grid{grid-template-columns:repeat(2,minmax(0,1fr))}.lens-grid>button{padding:16px;min-height:170px}.lens-grid .badge{font-size:10px;white-space:normal}}

.home-sections{position:sticky;top:0;z-index:6;display:flex;align-self:auto;gap:8px;flex-wrap:wrap;margin:22px 0 20px;padding:10px;border:1px solid var(--line);border-radius:12px;background:var(--bar);box-shadow:0 6px 18px #182c4410}.home-sections button{padding:12px 18px;min-height:44px;border-radius:8px;color:var(--ink);font-size:13px}.home-sections button[aria-pressed="true"]{background:var(--primary);color:var(--on-primary)}.home-pane[hidden]{display:none}.home-pane .research-launchpad{margin-top:0}body[data-view="home"]:not([data-home-section="reference"]) #general-research{display:none}.home-pane>.home-paths,.home-pane>.home-evidence-guide{border-top:0}.home-pane>.home-compare{margin-top:0}@media(max-width:600px){.home-sections{gap:4px;padding:7px}.home-sections button{font-size:12px;padding:10px 12px}}

/* Session research desk */
.reading-list{padding:30px;border:1px solid var(--line);border-radius:16px;background:var(--surface)}.reading-list h2{font-size:clamp(28px,4vw,46px);margin:12px 0}.reading-card{padding:24px;border:1px solid var(--line);border-radius:12px}.reading-card button{margin:12px 10px 0 0}.reading-pick{margin:0 12px 12px;padding:10px;border:1px solid var(--line);border-radius:8px;background:transparent;color:var(--green);cursor:pointer}.reading-pick[aria-pressed="true"]{background:var(--pale)}.reading-desk-link{margin:0 0 18px;padding:12px 18px;border-radius:10px;border:1px solid var(--line);background:var(--surface);color:var(--ink);cursor:pointer}

/* Cycle 1: a research-first editorial entrance. */
body[data-view="home"] main{display:flex;flex-direction:column}
body[data-view="home"] .intro{order:0;padding:20px 0;align-items:center}
body[data-view="home"] .intro h1{font-size:25px;letter-spacing:-.6px}
body[data-view="home"] .intro .edition,body[data-view="home"] .intro>div>p{display:none}
body[data-view="home"] .overview{order:1}
body[data-view="home"] #home-view{order:2}
body[data-view="home"] .review-banner{order:3;margin-top:12px;font-size:12px}
body[data-view="home"] #general-research{order:4}
body[data-view="home"] footer{order:5}
body[data-view="home"] #get-app{margin-top:10px;max-width:270px;min-height:36px;padding:8px 14px;border-radius:8px;box-shadow:none;background:var(--panel);color:var(--ink)}
body[data-view="home"] #get-app .get-app-text small,body[data-view="home"] #get-app .get-app-new{display:none}
.home-pane .research-launchpad{position:relative;isolation:isolate;overflow:hidden;border-radius:4px 28px 28px 28px;background:#102a43;box-shadow:0 24px 70px #0a203228;grid-template-columns:minmax(0,1.4fr) minmax(260px,1fr);padding:clamp(24px,4vw,64px)}
.research-launchpad:before{content:"";position:absolute;inset:0;z-index:-1;background:radial-gradient(ellipse at 0 0,#275f7a 0,transparent 65%),repeating-linear-gradient(90deg,transparent 0 79px,#ffffff04 80px 81px)}
.research-launchpad .home-welcome h2{font-size:clamp(38px,4.6vw,72px);line-height:1.06;letter-spacing:-2px}
.research-launchpad .home-welcome h2 em{font-weight:400;color:#a6dfce}
.research-launchpad .home-search-field{border:2px solid #95cfc0;box-shadow:0 0 0 6px #a6dfce12;border-radius:10px}
.research-launchpad .home-search-field button{background:#a6dfce;color:#102a43;font-weight:750}
.research-launchpad .launch-routes>button,.research-launchpad .launch-routes>a{border-radius:2px 14px 14px 14px;min-height:92px;background:#ffffff05}
.home-sections{box-shadow:none;border:0;border-radius:0;padding:8px 0;background:var(--bg)}
@media(max-width:600px){
 body[data-view="home"] .intro{padding:12px 0;gap:10px}
 body[data-view="home"] .intro h1{font-size:20px}
 body[data-view="home"] .intro .snapshot{margin:0;padding:0;text-align:right}
 body[data-view="home"] .snapshot>strong,body[data-view="home"] .snapshot>.status-dot,body[data-view="home"] .snapshot>#snapshot-date{display:none}
 body[data-view="home"] #get-app{display:none}
 body[data-view="home"] .overview{padding:10px 0}
 .home-sections{flex-wrap:nowrap;overflow-x:auto;gap:4px;margin:8px 0 12px;scrollbar-width:thin}
 .home-sections button{flex-shrink:0;font-size:12px;padding:10px 13px}
 .home-pane .research-launchpad{display:block;padding:26px 22px;border-radius:4px 20px 20px 20px}
 .research-launchpad .home-welcome h2{font-size:40px;letter-spacing:-1.4px}
 .research-launchpad .home-welcome>p{font-size:14px;line-height:1.6}
 .research-launchpad .home-welcome .home-note{font-size:11px}
}

/* Cycle 2: explore mechanisms as a visual atlas. */
.pathway-heading{display:flex;justify-content:space-between;gap:24px;align-items:center;margin-bottom:26px}.pathway-heading h2{font:clamp(32px,4vw,54px)/1.1 Georgia,serif;margin:0 0 14px;letter-spacing:-1px}.pathway-heading p{color:var(--muted);line-height:1.7;max-width:560px}.pathway-total{font:64px Georgia,serif;color:var(--green);text-align:right}.pathway-total small{display:block;font:12px/1.5 system-ui;max-width:120px;color:var(--muted)}.pathway-search{display:grid;gap:10px;max-width:720px;font-size:13px;font-weight:650}.pathway-search input{padding:17px 20px;font:16px system-ui;color:var(--ink);background:var(--surface);border:1px solid var(--line);border-radius:12px;width:100%}.pathway-atlas .feed-note{margin:16px 0 24px}.pathway-atlas .home-path-grid{gap:18px}.pathway-atlas .pathway-card{gap:16px;justify-content:flex-start;padding:24px;min-height:245px;border-radius:2px 18px 18px 18px}.pathway-card:hover{border-color:var(--green);transform:translateY(-2px)}.pathway-card-top{display:flex;width:100%;justify-content:space-between}.pathway-card strong{font:25px/1.25 Georgia,serif;letter-spacing:-.4px}.pathway-names{line-height:1.6}.pathway-signal{display:flex;width:100%;height:7px;gap:3px;margin-top:auto}.pathway-signal i{flex-basis:0;border-radius:2px}.pathway-signal .H{background:var(--human)}.pathway-signal .P{background:var(--pre)}.pathway-signal .T{background:var(--theory)}.pathway-signal .A{background:var(--anec)}.pathway-signal .U{background:var(--unknown)}.pathway-card .pathway-classes{font-size:10px;line-height:1.7}.pathway-atlas .empty{grid-column:1/-1}@media(max-width:600px){.pathway-atlas .home-path-grid{grid-template-columns:1fr}.pathway-total{font-size:48px}.pathway-heading{align-items:flex-start}.pathway-atlas .pathway-card{min-height:220px}.pathway-heading h2{font-size:34px}}

/* Cycle 3: an instant research finder, without leaving the launchpad. */
.home-search-matches:empty{display:none}.home-search-matches{margin-top:18px;text-align:left}.home-match-status{font-size:12px!important;line-height:1.6!important;color:#c5dbeb!important}.home-search-matches ul{list-style:none;margin:12px 0 0;padding:0;border:1px solid #7295ae;border-radius:12px;overflow:hidden;background:#102538}.home-search-matches li+li{border-top:1px solid #456079}.home-search-matches button{display:flex;width:100%;justify-content:space-between;gap:16px;align-items:center;text-align:left;padding:16px;color:#edf7ff;min-height:72px}.home-search-matches button:hover,.home-search-matches button:focus-visible{background:#24475f}.home-search-matches strong{font-size:16px}.home-search-matches small{display:block;margin-top:6px;color:#bbd2e3;font-size:12px}.home-match-classes{max-width:45%;font-size:11px;line-height:1.9;text-align:right}.home-match-classes .badge{white-space:normal}@media(max-width:600px){.home-search-matches button{padding:14px;align-items:flex-start}.home-match-classes{max-width:40%}.home-match-classes .badge{font-size:9px}.home-search-matches small{font-size:11px}}

/* Cycle 4: a returnable, opt-in research desk. */
.reading-list{border-radius:4px 24px 24px 24px;padding:clamp(22px,4vw,48px)}.reading-list>h2{font-family:Georgia,serif;font-weight:400;letter-spacing:-1px}.reading-list>p{max-width:650px;line-height:1.7;color:var(--muted)}.desk-storage{display:grid;grid-template-columns:1.2fr 1fr;gap:12px 30px;background:var(--panel);padding:24px;border-radius:14px;margin:26px 0}.desk-storage h3{font-size:19px;margin:0 0 10px}.desk-storage p{font-size:13px;line-height:1.7;margin:0;color:var(--muted)}.desk-storage label{display:flex;gap:12px;align-items:center;font-size:14px;line-height:1.6;cursor:pointer}.desk-storage input{width:22px;height:22px;accent-color:var(--primary);flex-shrink:0}.desk-storage .desk-storage-status{grid-column:1/-1;padding-top:12px;border-top:1px solid var(--line)}.reading-list .reading-card{display:flex;flex-direction:column;background:var(--bg)}.reading-card h3{font:27px Georgia,serif;margin:0 0 12px}.reading-card p{color:var(--muted);line-height:1.7}.reading-card [data-reading-open]{padding:14px;border-radius:8px;background:var(--primary);color:var(--on-primary);margin-top:auto}.reading-card [data-reading-toggle]{min-height:44px;color:var(--green)}@media(max-width:700px){.desk-storage{grid-template-columns:1fr;padding:20px}.reading-list .home-path-grid{grid-template-columns:1fr}}

/* Cycle 5: a full-width research article with a reversible focus mode. */
.focus-reading-bar{position:sticky;top:0;z-index:12;display:flex;justify-content:space-between;align-items:center;gap:16px;padding:16px 20px;background:var(--bar);border:1px solid var(--line);border-radius:12px;margin-bottom:32px;box-shadow:0 8px 28px #10253812}.focus-reading-bar>span{font-size:11px;font-weight:700;letter-spacing:1px}.focus-reading-bar button{padding:10px 14px;border-radius:8px;background:var(--primary);color:var(--on-primary);min-height:44px;font-size:13px}.reading-focus .intro,.reading-focus .overview,.reading-focus .review-banner,.reading-focus .filters,.reading-focus .catalog,.reading-focus #evidence-chart,.reading-focus #quick-filters,.reading-focus #active-filters,.reading-focus #since-visit,.reading-focus #explorer-view>.searchbar,.reading-focus #explorer-view>.mobile-tools,.reading-focus #mobile-tools-toggle{display:none!important}.reading-focus #workspace{display:block;border:0;min-height:0}.reading-focus #detail{max-width:880px;margin:24px auto;padding:0 0 60px;border:0}.reading-focus #detail h2{font-size:clamp(36px,5vw,60px);letter-spacing:-1px}.reading-focus .record{padding:clamp(22px,4vw,40px);margin:20px 0;border-radius:4px 18px 18px 18px}.reading-focus .record h3{font:25px/1.4 Georgia,serif}.reading-focus .record p{font-size:16px;line-height:1.85}.reading-focus .record .context,.reading-focus .record .limitation{font-size:13px!important;line-height:1.8}.reading-focus .record-group>summary{padding:18px}.reading-focus .badge{font-size:11px}.reading-focus .detail-reading-nav{display:none}.reading-focus .protocol-fields dt{font-size:13px}.reading-focus .protocol-fields dd{font-size:15px;line-height:1.8}@media(max-width:600px){.focus-reading-bar{padding:10px 14px}.focus-reading-bar>span{max-width:55%;line-height:1.5}.reading-focus .record p{font-size:15px}.reading-focus .record h3{font-size:23px}}

/* Cycle 6: a thumb-reachable mobile research workspace. */
.research-dock{display:none}
@media(max-width:600px){
 body:has(.research-dock){padding-bottom:90px}
 .research-dock{position:fixed;display:grid;grid-template-columns:repeat(4,minmax(0,1fr));inset:auto 0 0;z-index:14;margin:0;padding:8px 10px max(8px,env(safe-area-inset-bottom));height:auto;gap:6px;background:var(--bar);border-top:1px solid var(--line);box-shadow:0 -6px 25px #10253815}
 .research-dock button{display:flex;flex-direction:column;gap:5px;align-items:center;justify-content:center;padding:9px 4px;min-height:58px;font-size:11px;font-weight:600;border-radius:10px;color:var(--muted)}
 .research-dock button>span{font-size:23px;line-height:1}
 .research-dock button[aria-current="page"]{background:var(--primary);color:var(--on-primary)}
 .has-compare-tray .compare-tray{bottom:90px}
 body.has-compare-tray{padding-bottom:340px}
 .reading-focus .research-dock{display:none}
 .reading-focus:has(.research-dock){padding-bottom:0}
 .reading-focus .compare-tray{bottom:8px}
}
@media print{.research-dock{display:none!important}}

/* Cycle 8: inspect differences with stable comparison context. */
.compare-head h2{font:clamp(32px,4vw,52px)/1.1 Georgia,serif;letter-spacing:-1px}.compare-controls{display:flex;align-items:center;gap:12px;flex-wrap:wrap;padding:22px;background:var(--panel);border:1px solid var(--line);border-radius:12px;margin:20px 0}.compare-controls>div{flex:1;min-width:240px}.compare-controls strong{font-size:18px}.compare-controls p{font-size:12px;line-height:1.7;color:var(--muted);margin:8px 0 0}.compare-controls button{min-height:46px;padding:12px 16px;border:1px solid var(--line);border-radius:8px;background:var(--surface);color:var(--green);font-size:12px}.compare-controls button[aria-pressed="true"]{background:var(--primary);color:var(--on-primary)}.compare-table{max-height:72vh;overflow:auto;scrollbar-width:thin;border-radius:12px}.compare-table .compare-headrow{position:sticky;top:0;z-index:4;background:var(--bar);box-shadow:0 2px 8px #10253812}.compare-headrow .compare-label{background:var(--bar)}.compare-headrow .compare-name{font-size:22px;padding:20px 14px}.compare-headrow .compare-name>span{font-size:11px;margin-top:8px}.compare-table[data-differences="true"] .compare-same{display:none}.compare-table:focus-visible{outline:3px solid var(--green);outline-offset:4px}@media(max-width:600px){.compare-controls{padding:18px}.compare-controls>div{min-width:100%}.compare-controls button{flex:1}.compare-headrow .compare-name{font-size:18px}.compare-table{max-height:65vh}}

/* Cycle 9: a source-attributed brief for the visitor's own notes. */
.detailtools [data-research-brief]{padding:11px 15px;border:1px solid var(--green);border-radius:8px;text-decoration:none;font-size:12px;font-weight:650;background:var(--pale);min-height:44px}.brief-copy{padding:13px 18px;border-radius:8px;color:var(--on-primary);background:var(--primary);font-size:14px;min-height:46px}.brief-intro{font-size:14px;line-height:1.8;color:var(--muted)}.research-brief-text{display:block;width:100%;min-height:390px;padding:20px;border:1px solid var(--line);border-radius:12px;background:var(--surface);color:var(--ink);font:13px/1.8 ui-monospace,SFMono-Regular,Consolas,monospace;resize:vertical}.research-brief-text:focus-visible{outline:3px solid var(--green);outline-offset:3px}#brief-copy-status{font-size:13px;color:var(--green);line-height:1.7}

/* Keep the first research action clear of the mobile workspace dock. */
@media(max-width:600px){body[data-view="home"] .intro{display:flex!important;min-height:36px;padding:8px 0!important}body[data-view="home"] .intro h1{position:absolute;width:1px;height:1px;margin:-1px;padding:0;overflow:hidden;clip:rect(0,0,0,0);white-space:nowrap}body[data-view="home"] .intro .snapshot{margin-left:auto}.research-launchpad .home-welcome h2{font-size:36px}.home-pane .research-launchpad{padding:22px}}

/* Cycle 11: the library as an evidence matrix. */
.catalog-mode{display:flex;gap:8px;padding:0 0 20px;flex-wrap:wrap}.catalog-mode button{padding:12px 18px;border:1px solid var(--line);background:var(--surface);border-radius:8px;min-height:44px;font-size:13px}.catalog-mode button[aria-pressed="true"]{background:var(--primary);color:var(--on-primary)}.evidence-mode .cataloglabels{display:none}.evidence-matrix{position:relative;max-width:100%;overflow:auto;border:1px solid var(--line);border-radius:14px;background:var(--surface)}.evidence-matrix table{width:100%;border-collapse:separate;border-spacing:0;min-width:660px;text-align:left}.matrix-guide{margin:0;text-align:left;padding:20px;line-height:1.8;font-size:13px;color:var(--muted);background:var(--panel)}.evidence-matrix th,.evidence-matrix td{padding:16px 14px;border-bottom:1px solid var(--line)}.evidence-matrix thead th{background:var(--bar);text-align:center}.evidence-matrix tr>th:first-child{position:sticky;left:0;z-index:1;background:var(--surface);min-width:190px}.evidence-matrix th button{font:20px/1.3 Georgia,serif;text-align:left;color:var(--green);padding:0;min-height:44px}.evidence-matrix th small{display:block;font-size:11px;color:var(--muted);font-weight:400}.evidence-matrix td{text-align:center}.evidence-matrix td button{min-width:58px;min-height:44px;border:1px solid var(--line);border-radius:8px;font-size:19px;background:var(--pale);color:var(--green)}.evidence-matrix td button:hover{border-color:var(--green)}.evidence-matrix td button span{font-size:11px}.evidence-matrix .badge{white-space:normal}.evidence-matrix tbody tr:hover td{background:var(--bg)}

/* Cycle 12: find a passage without losing the research context. */
.record-search{display:grid;grid-template-columns:1fr auto;align-items:center;gap:10px 16px;margin:24px 0;padding:22px;background:var(--panel);border:1px solid var(--line);border-radius:14px}.record-search label{font-size:14px;font-weight:650}.record-search input{grid-column:1/-1;grid-row:2;font-size:16px;min-height:50px;padding:14px 16px;border:1px solid var(--line);border-radius:8px;background:var(--surface);color:var(--ink);width:100%;min-width:0}.record-search>span{font-size:11px;color:var(--muted)}@media(max-width:600px){.record-search{padding:18px;grid-template-columns:1fr}.record-search>span{grid-row:3}.record-search label{font-size:13px}}

/* Cycle 13: useful exits from an over-filtered search. */
.filter-recovery{grid-column:1/-1;padding:clamp(24px,4vw,44px);border:1px solid var(--line);background:var(--surface);border-radius:4px 20px 20px 20px}.filter-recovery h3{font:clamp(28px,3vw,40px)/1.2 Georgia,serif;letter-spacing:-.6px;margin:16px 0}.filter-recovery>p{max-width:650px;color:var(--muted);font-size:14px;line-height:1.8}.recovery-choices{display:grid;gap:12px;margin:26px 0}.recovery-choices button{display:flex;justify-content:space-between;gap:20px;text-align:left;align-items:center;padding:20px;background:var(--panel);border:1px solid var(--line);border-radius:10px;min-height:74px}.recovery-choices button>span{font-size:13px;line-height:1.7;overflow-wrap:anywhere}.recovery-choices strong{font-size:14px;white-space:nowrap;color:var(--green)}.recovery-choices button:hover{border-color:var(--green)}.filter-recovery>.textbutton{min-height:44px;font-size:13px}@media(max-width:600px){.recovery-choices button{display:block}.recovery-choices strong{display:block;margin-top:12px}}

/* Cycle 14: trace a source into the records that cite it. */
.source-trail{margin-top:28px;padding-top:26px;border-top:1px solid var(--line)}.source-trail>h3{font:28px/1.3 Georgia,serif;letter-spacing:-.4px;margin:12px 0}.source-trail>p{font-size:13px;line-height:1.8;color:var(--muted)}.source-trail-group{border:1px solid var(--line);border-radius:12px;background:var(--surface);margin:14px 0;overflow:hidden}.source-trail-group>summary{cursor:pointer;padding:18px;font-size:16px;font-weight:650;background:var(--panel)}.source-trail-group>summary span{font-size:11px;margin-left:12px;color:var(--muted)}.source-trail-group article{padding:22px;border-top:1px solid var(--line)}.source-trail-group h4{font:21px/1.4 Georgia,serif;margin:14px 0}.source-trail-group article>p{font-size:13px;line-height:1.85}.source-trail-group .trail-limit{border-left:3px solid var(--line);padding-left:14px;color:var(--muted)}.source-trail-group button{padding:12px 16px;border-radius:8px;background:var(--pale);color:var(--green);min-height:44px;margin-top:12px;font-weight:650}

/* Cycle 18: learn evidence boundaries from a real record. */
.evidence-tour{padding:clamp(24px,4vw,44px);margin:28px 0;border:1px solid var(--line);border-radius:4px 22px 22px 22px;background:var(--panel)}.evidence-tour>h2{font:clamp(32px,4vw,48px)/1.15 Georgia,serif;letter-spacing:-1px;margin:14px 0 20px}.evidence-tour>p{font-size:14px;line-height:1.85;color:var(--muted);max-width:720px}.evidence-tour-choices{display:flex;gap:8px;flex-wrap:wrap;margin:26px 0}.evidence-tour-choices button{min-height:44px;padding:12px 16px;border:1px solid var(--line);border-radius:8px;background:var(--surface);color:var(--ink);font-size:12px}.evidence-tour-choices button[aria-pressed="true"]{background:var(--primary);color:var(--on-primary)}.evidence-example{background:var(--surface);border:1px solid var(--line);border-radius:14px;overflow:hidden}.example-heading{display:flex;align-items:center;gap:16px;padding:20px 26px;border-bottom:1px solid var(--line)}.example-heading>span:not(.badge){font-size:12px;color:var(--muted)}.example-reading{display:grid;grid-template-columns:1.4fr 1fr 1fr}.example-reading>section{padding:26px;min-width:0}.example-reading>section+section{border-left:1px solid var(--line)}.example-step{font-size:10px;letter-spacing:1.1px;font-weight:700;color:var(--green)}.example-reading h3{font:23px/1.4 Georgia,serif;margin:18px 0}.example-reading p{font-size:13px;line-height:1.9;color:var(--ink);overflow-wrap:anywhere}.example-citations{padding:24px 26px;border-top:1px solid var(--line)}.example-citations>strong{font-size:12px}.example-citations>.textbutton{margin-top:16px;min-height:44px;font-size:12px}@media(max-width:850px){.example-reading{grid-template-columns:1fr}.example-reading>section+section{border-left:0;border-top:1px solid var(--line)}.example-reading>section{padding:22px}}

/* Cycle 19: the owner Review workspace as a decision cockpit. */
body[data-view="review"] .intro,body[data-view="review"] .overview{display:none}.claim-review .claim-review-heading{padding:36px 0 20px;align-items:center;border-bottom:1px solid var(--line)}.claim-review .claim-review-heading>h2{font:clamp(38px,5vw,60px)/1.1 Georgia,serif;font-weight:400;letter-spacing:-1px;margin:0}.claim-review>.claim-review-note{font-size:14px;line-height:1.9;max-width:1050px;padding:18px 0}.review-workflow-heading{padding:30px 0 20px}.review-workflow-heading>h3{font:clamp(30px,4vw,44px)/1.2 Georgia,serif;letter-spacing:-.8px;font-weight:400;margin:14px 0}.review-workflow-heading>p{color:var(--muted);font-size:13px;line-height:1.8}.claim-review .review-jump{display:grid;grid-template-columns:repeat(4,minmax(0,1fr));gap:14px;margin:0 0 44px;padding:0;height:auto;align-self:auto}.claim-review .review-jump>a{position:relative;display:flex;flex-direction:column;gap:15px;align-items:flex-start;padding:24px;min-height:200px;border:1px solid var(--line);border-radius:3px 16px 16px 16px;background:var(--surface);text-decoration:none;color:var(--ink);white-space:normal}.review-queue-number{font:28px Georgia,serif;color:var(--green)}.review-jump strong{font-size:18px;font-weight:650}.review-jump small{font-size:12px;line-height:1.8;color:var(--muted);padding-right:15px}.review-queue-arrow{position:absolute;right:20px;top:26px;color:var(--green)}.claim-review .review-jump>a:hover{border-color:var(--green);background:var(--pale)}.claim-review>.review-section,.claim-review>.audit-panel{padding:clamp(22px,3vw,36px);margin:26px 0;border:1px solid var(--line);border-radius:16px;background:var(--surface);scroll-margin-top:20px}.claim-review>.review-section>h3,.claim-review .audit-panel h3{font:30px/1.3 Georgia,serif;font-weight:400;margin-top:0}@media(max-width:1000px){.claim-review .review-jump{grid-template-columns:repeat(2,minmax(0,1fr))}}@media(max-width:600px){.claim-review .review-jump{gap:10px}.claim-review .review-jump>a{padding:18px;min-height:200px}.review-jump strong{font-size:16px}.review-queue-arrow{right:16px;top:20px}.review-jump small{padding-right:0}.claim-review>.claim-review-note{font-size:13px}.claim-review .claim-review-heading{display:block}.public-atlas-link{margin-top:16px;display:inline-flex}}

/* Cycle 20: durable, context-preserving links to individual claims. */
.record[id]{scroll-margin-top:110px}.record[data-linked-record="true"]{border:2px solid var(--green);box-shadow:0 0 0 5px var(--pale)}.record[data-linked-record="true"]:before{content:"LINKED RECORD";display:block;font-size:10px;font-weight:750;letter-spacing:1.2px;color:var(--green);margin-bottom:18px}.claim-actions{display:flex;flex-wrap:wrap;align-items:center;gap:8px 18px;margin-top:20px;padding-top:14px;border-top:1px solid var(--line)}.claim-actions a,.claim-actions button{display:inline-flex;align-items:center;min-height:44px;font-size:11px;color:var(--green);text-decoration:underline;text-underline-offset:3px;padding:6px 0}.claim-actions [role="status"]{font-size:11px;color:var(--muted)}.claim-link-input{width:100%;min-height:48px;padding:14px;border:1px solid var(--line);border-radius:8px;background:var(--surface);color:var(--ink);font-size:14px}.cp-record-link{display:inline-flex;align-items:center;min-height:44px;font-size:12px;color:var(--green);margin-top:16px}@media(max-width:600px){.record[id]{scroll-margin-top:160px}}@media print{.claim-actions{display:none!important}}

/* Brand mark: the molecule symbol (public-edition/brand), drawn in currentColor inside the coloured tile. */
.brandmark{display:grid;place-items:center;padding:5px;letter-spacing:0;line-height:0;flex-shrink:0}.brandmark svg{display:block;width:100%;height:100%}

/* UX cycle 1: Editorial search landing */
.research-launchpad{border:1px solid var(--line);border-radius:24px;padding:clamp(22px,4vw,64px);background:radial-gradient(ellipse at top right,var(--pale),transparent 70%),var(--surface)}.home-welcome h2{font-size:clamp(40px,5.8vw,82px);line-height:1.02;letter-spacing:-2px}.home-search-field{box-shadow:0 12px 32px #152d4214}.home-search-field button{min-height:52px}.home-welcome>p{font-size:17px;max-width:46ch}

/* UX cycle 2: Guided research journey */
.research-journey{display:grid;grid-template-columns:repeat(3,1fr);gap:1px;background:var(--line);border:1px solid var(--line);border-radius:16px;overflow:hidden;margin:28px 0}.research-journey button{background:var(--surface);padding:24px;text-align:left;min-height:150px}.research-journey strong,.research-journey small{display:block;margin-top:12px}.research-journey strong{font:24px Georgia,serif}.research-journey small{line-height:1.6;color:var(--muted)}@media(max-width:600px){.research-journey{grid-template-columns:1fr}.research-journey button{min-height:0}}

/* UX cycle 3: Live library sampler */
.library-sampler{margin:40px 0}.sampler-grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:16px}.sampler-grid article{padding:24px;border:1px solid var(--line);border-radius:16px;background:var(--surface)}.sampler-grid h3{font:26px Georgia,serif}.sampler-grid p{line-height:1.6;color:var(--muted)}.sampler-grid button{padding:12px 0;color:var(--green);font-weight:700}@media(max-width:700px){.sampler-grid{grid-template-columns:1fr}}

/* UX cycle 4: Research card directory */
.directory-mode #results{display:grid;grid-template-columns:repeat(auto-fit,minmax(min(100%,260px),1fr));gap:16px;padding:18px}.directory-mode .compound-choice{border:1px solid var(--line);border-radius:16px;overflow:hidden;background:var(--surface)}.directory-mode .compoundrow{min-height:235px;border-bottom:0}.directory-mode .rowtop strong{font:26px Georgia,serif}.directory-mode .rowpath{font-size:12px;line-height:1.6}.directory-cta{display:block;color:var(--green);font-weight:700;font-size:12px;margin:16px 0 10px}.compound-choice:focus-within{outline:2px solid var(--green);outline-offset:3px}

/* UX cycle 5: Interactive evidence portrait */
.evidence-portrait{margin:24px 0;padding:20px;border:1px solid var(--line);border-radius:16px;background:var(--surface)}.evidence-portrait>div{display:flex;flex-wrap:wrap;gap:8px;margin:12px 0}.evidence-portrait button{flex:1 1 95px;padding:12px;border:1px solid var(--line);border-radius:8px}.evidence-portrait button[aria-pressed="true"]{outline:2px solid var(--green)}.evidence-portrait b{display:block;font:30px Georgia,serif;margin-bottom:8px}.evidence-portrait p{font-size:12px;color:var(--muted);line-height:1.6}

/* UX cycle 6: Limitations as a checkpoint */
.record .limitation{padding:18px 20px!important;border:1px solid var(--line);border-left:4px solid var(--unknown);border-radius:0 12px 12px 0;background:var(--panel,var(--pale));font-size:13px!important;line-height:1.8!important}.record .limitation b{display:block;font-size:10px;letter-spacing:1px;text-transform:uppercase;margin-bottom:6px}.record h3{font-size:21px;line-height:1.35}.record{box-shadow:0 5px 18px #172b3a06}

/* UX cycle 7: Reading desk to comparison */
.desk-compare{padding:28px;background:var(--pale);border:1px solid var(--line);border-radius:18px;display:flex;justify-content:space-between;align-items:center;gap:24px;margin:24px 0}.desk-compare button{padding:14px 20px;background:var(--green);color:var(--surface);border-radius:8px}.desk-compare p{line-height:1.6}@media(max-width:600px){.desk-compare{display:block}.desk-compare button{margin-top:12px}}

/* UX cycle 8: Comparison starting line */
.compare-start{padding:clamp(24px,4vw,48px);border:1px solid var(--line);border-radius:20px;background:var(--surface);margin:24px 0}.compare-start h3{font:clamp(28px,4vw,48px) Georgia,serif;margin:12px 0}.compare-start p{max-width:65ch;line-height:1.8;color:var(--muted)}.compare-start>div:last-child{display:flex;gap:10px;flex-wrap:wrap}.compare-start button{padding:14px;border:1px solid var(--line);border-radius:8px;color:var(--green)}

/* UX cycle 9: Plain-language reference launch */
.reference-launch{padding:32px;border:1px solid var(--line);border-radius:20px;background:var(--surface);margin:24px 0}.reference-launch h2{font:36px Georgia,serif}.reference-launch ol{display:grid;grid-template-columns:repeat(3,1fr);gap:32px;padding-left:22px}.reference-launch li{padding-left:8px;line-height:1.7}.reference-launch li span{display:block;color:var(--muted);margin-top:8px}.reference-launch button{padding:14px 0;color:var(--green);font-weight:700}@media(max-width:700px){.reference-launch ol{grid-template-columns:1fr}}

/* UX cycle 10: Compound next-step station */
.research-next{margin-top:32px;padding:32px;border-radius:20px;border:1px solid var(--line);background:var(--pale)}.research-next h3{font:32px Georgia,serif;margin:12px 0 24px}.research-next>div{display:flex;flex-wrap:wrap;gap:12px}.research-next button{padding:14px 18px;border:1px solid var(--green);border-radius:8px;background:var(--surface);color:var(--green);font-weight:650}.research-next p{font-size:12px;line-height:1.7;color:var(--muted)}@media(prefers-reduced-motion:no-preference){.research-journey button,.sampler-grid article,.directory-mode .compound-choice{transition:transform .18s ease,box-shadow .18s ease}.research-journey button:hover,.sampler-grid article:hover,.directory-mode .compound-choice:hover{transform:translateY(-3px);box-shadow:0 8px 22px #172b3a12}}@media print{.research-journey,.research-next,.desk-compare{display:none}}

.review-banner{margin:20px 0;padding:16px 20px;border:1px solid #bba775;border-radius:8px;background:#fcf7e8;color:#514523;font-size:14px;line-height:1.6}.private{font-size:10px;letter-spacing:.06em}
.mobile-tools,.mobile-filter-done{display:none}
@media(max-width:900px){
 main{padding:0 16px}.topbar{height:auto;min-height:0;gap:12px;padding:16px;flex-wrap:wrap}.brand{flex:1;min-width:0}.brandmark{flex-shrink:0}.brand small{font-size:11px}.private{font-size:10px;max-width:135px;line-height:1.5;text-align:center;white-space:normal}nav{order:3;width:100%;height:auto;margin:0;gap:4px 16px;flex-wrap:wrap}.navitem{min-height:44px;font-size:14px}
 .intro{display:block;padding:24px 0 18px}.intro h1{font-size:32px;line-height:1.15;overflow-wrap:break-word}.intro p{font-size:14px}.eyebrow{font-size:11px}.edition{display:none}.snapshot{margin-top:14px;font-size:12px}.snapshot strong{display:inline}.snapshot>span:not(.status-dot){display:inline;margin-left:6px}.snapshot .textbutton{display:block;font-size:12px;min-height:44px}.review-banner{margin:16px 0 0;padding:12px 14px;font-size:12px;line-height:1.6}
 .overview{gap:14px;flex-wrap:wrap;font-size:11px;padding:14px 0}.overview strong{font-size:17px}.legend{width:100%;margin:0;gap:10px 14px;flex-wrap:wrap;font-size:11px}
 .searchbar{display:grid;grid-template-columns:minmax(0,1fr) auto;gap:8px;padding:18px 0 12px}.searchwrap{height:48px;min-width:0;padding:0 12px;gap:8px}.searchwrap input{font-size:16px}.searchwrap kbd{display:none}.searchwrap svg{flex-shrink:0}.subtle{min-height:48px;font-size:12px;padding:8px}
 .mobile-tools{display:grid;grid-template-columns:minmax(0,1fr) auto;gap:10px;align-items:center;margin:0 0 16px}.mobile-tools label{grid-column:1/-1;display:block;font-size:12px;font-weight:600}.mobile-tools select{display:block;width:100%;max-width:100%;margin-top:7px;padding:12px;border:1px solid var(--line);border-radius:8px;background:var(--surface);color:var(--ink);font-size:16px;min-height:48px}.mobile-tools button{min-height:44px;padding:10px 16px;border:1px solid var(--line);border-radius:8px;background:var(--surface);font-size:14px}.mobile-tools button[aria-expanded=true]{background:var(--pale);border-color:var(--green)}.mobile-tools span{font-size:12px;color:var(--muted)}
 .layout{display:block;min-height:0;border-top:0}.filters{display:none;padding:16px;background:var(--surface);border:1px solid var(--line);border-radius:10px;margin-bottom:20px}.filters.mobile-open{display:grid;grid-template-columns:minmax(0,1fr);gap:16px}.filterheading{grid-column:auto;font-size:11px;margin:0}#pathways{grid-column:auto;display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:6px;overflow:visible;padding:0}.pathbutton{width:100%;min-width:0;min-height:44px;font-size:12px;white-space:normal;padding:9px;text-align:left;margin:0}.pathbutton span:first-child{min-width:0;overflow-wrap:break-word}.filtergroup{margin:0;min-width:0}.filtergroup label{font-size:13px}.filtergroup select{font-size:16px;min-height:48px;padding:10px;max-width:100%}.filter-note{font-size:12px;margin:0;grid-column:auto}.mobile-filter-done{display:block;min-height:44px;border-radius:8px;background:var(--green);color:white;font-size:14px;padding:10px}
 .catalog{display:none}.detail{border:0;padding:4px 0 24px;min-width:0;scroll-margin-top:12px}.detail h2{font-size:30px;overflow-wrap:break-word}.detailpath{font-size:11px}.compoundtype{font-size:11px}.target{font-size:14px}.gap{font-size:13px;line-height:1.65;padding:14px;margin:16px 0}.gap strong{font-size:10px}.tabs{gap:0;display:grid;grid-template-columns:repeat(3,minmax(0,1fr));margin:18px 0 12px}.tab{min-height:48px;padding:10px 4px;font-size:13px;line-height:1.4}.matchnote{font-size:12px;line-height:1.65}.record{padding:16px;border-radius:10px;margin:14px 0}.record h3{font-size:17px;line-height:1.4}.record p{font-size:14px;line-height:1.75}.record .context{font-size:12px!important;line-height:1.65}.badge{font-size:11px;padding:5px 8px}.strength{font-size:11px}.protocolbox{font-size:14px;line-height:1.7;padding:12px}.protocolbox small{font-size:10px;letter-spacing:.6px}.limitation b{font-size:11px}.refs{display:grid;grid-template-columns:minmax(0,1fr);gap:8px}.ref{min-height:44px;padding:10px;text-align:left;font-size:12px;line-height:1.5;overflow-wrap:anywhere}
 .sourcesview{padding:12px 0}.sourcesview p,.sourcecard p{font-size:14px}.sourcesview h2{font-size:26px}.sourcesgrid{grid-template-columns:minmax(0,1fr)}.sourcecard h3{font-size:16px}.sourcecard .textbutton{font-size:13px;min-height:44px}.scopebox{padding:16px}.readerhead{padding:16px;gap:10px}.readerhead h2{font-size:21px;overflow-wrap:anywhere}.iconbutton{width:44px;height:44px}.readerhead .eyebrow{font-size:10px}dialog{width:calc(100% - 24px);max-height:90dvh;border-radius:12px}#reader-body{padding:0 16px 22px;font-size:14px}#reader-controls{padding:8px 16px}.source-status{font-size:12px}footer{display:block;font-size:11px;line-height:1.8}footer span{display:block}
}
@media(max-width:360px){.private{max-width:102px;font-size:9px;padding:5px}.brand{gap:8px;font-size:9px}.brand small{font-size:10px}.intro h1{font-size:29px}.overview{gap:10px}.legend{gap:8px}.tab{font-size:12px}}
#mobile-tools-toggle{display:none}@media(max-width:900px){#explorer-view.compound-focus>.searchbar,#explorer-view.compound-focus>.quick-filters,#explorer-view.compound-focus>.active-filters,#explorer-view.compound-focus>.reading-controls{display:none}#explorer-view.has-compound #mobile-tools-toggle{display:inline-flex}#explorer-view.compound-focus>.mobile-tools{margin-top:12px}}
.news-strip{background:var(--green);color:#fff;display:flex;align-items:center;gap:16px;padding:0 4%;min-height:54px}.news-label{font-size:11px;font-weight:700;letter-spacing:.1em;white-space:nowrap}.news-window{flex:1;min-width:0;overflow:hidden}.news-track{display:flex;width:max-content;animation:atlas-news-scroll var(--news-duration,300s) linear infinite;animation-play-state:paused}.news-strip.is-crawling .news-track{animation-play-state:running}.news-group{display:flex;align-items:center;gap:40px;padding-right:40px;flex-shrink:0}.news-item{color:inherit;white-space:nowrap;text-decoration:none;font-size:13px;display:flex;align-items:center;gap:10px;min-height:50px}.news-item:hover{text-decoration:underline}.news-category{font-size:10px;text-transform:uppercase;letter-spacing:.06em;background:#ffffff20;padding:4px 7px;border-radius:4px}.news-date{opacity:.8;font-size:11px}.news-strip button{color:inherit;min-height:44px;padding:8px;font-size:12px;white-space:nowrap}.news-strip:hover .news-track,.news-strip:focus-within .news-track,.news-strip.is-paused .news-track{animation-play-state:paused}.news-archive{padding:12px 4%;border-bottom:1px solid var(--line);background:var(--surface)}.news-archive summary{color:var(--green);font-size:12px;cursor:pointer;min-height:44px;padding:13px 0;display:list-item}.news-archive article{max-width:950px;padding:18px 0;border-bottom:1px solid var(--line)}.news-archive h3{font-size:16px;margin:6px 0}.news-archive p{line-height:1.65;margin:7px 0}.news-archive small{color:var(--muted)}@keyframes atlas-news-scroll{to{transform:translateX(-50%)}}@media(prefers-reduced-motion:reduce){.news-track{animation:none}.news-window{overflow-x:auto}.news-group[aria-hidden]{display:none}}@media(max-width:600px){.news-strip{gap:8px;padding:0 16px}.news-label{font-size:10px}.news-date{display:none}.news-item{font-size:13px}.news-archive{padding:12px 16px}}
.news-window{mask-image:linear-gradient(90deg,transparent,#000 24px,#000 calc(100% - 24px),transparent)}.news-all{color:inherit;white-space:nowrap;font-size:12px;min-height:44px;display:inline-flex;align-items:center;text-decoration:underline;text-underline-offset:3px}@media(max-width:600px){.news-label{display:none}}
.news-page{max-width:900px}.news-page .news-filters{display:flex;flex-wrap:wrap;gap:6px;margin:8px 0 16px;padding:0;list-style:none}.news-page .news-filters a{display:inline-flex;align-items:center;min-height:36px;padding:4px 12px;border:1px solid var(--line);border-radius:999px;color:var(--ink);text-decoration:none}.news-page article{padding:16px 0;border-bottom:1px solid var(--line)}.news-page article h3{font-size:1.02rem;margin:6px 0}.news-page article h3 a{color:var(--green)}.news-page small{color:var(--muted)}.news-page h2{scroll-margin-top:12px}
.news-item .new-badge{margin:0 2px 0 0}.news-new-n{font-weight:700}.news-page small .new-badge{margin:0 6px 0 0}
/* Blue and grey palette shared by the public day and night themes. */
:root{color-scheme:light;--bg:#edf0f4;--surface:#f7f9fc;--ink:#243447;--muted:#53667b;--line:#c7d1df;--green:#285e99;--pale:#dce7f5;--panel:#e3e9f1;--bar:#e7edf5;--primary:#315f91;--on-primary:#f3f7fd;--human:#285e99;--pre:#1d7566;--theory:#74509a;--anec:#9a5f17;--unknown:#6f7c8b}
:root[data-theme="dark"]{color-scheme:dark;--bg:#141a23;--surface:#1c2532;--ink:#dce4ef;--muted:#abbace;--line:#39495f;--green:#a1c5f3;--pale:#293c56;--panel:#253246;--bar:#1a2433;--primary:#365c8b;--on-primary:#f0f5fd;--human:#8fbcf2;--pre:#6fcfb8;--theory:#c1a2e6;--anec:#e2b26a;--unknown:#8a98ab}
/* No saved choice: follow the device setting. data-theme is set only after a visitor picks one. */
@media(prefers-color-scheme:dark){:root:not([data-theme="light"]){color-scheme:dark;--bg:#141a23;--surface:#1c2532;--ink:#dce4ef;--muted:#abbace;--line:#39495f;--green:#a1c5f3;--pale:#293c56;--panel:#253246;--bar:#1a2433;--primary:#365c8b;--on-primary:#f0f5fd;--human:#8fbcf2;--pre:#6fcfb8;--theory:#c1a2e6;--anec:#e2b26a;--unknown:#8a98ab}:root:not([data-theme="light"]) .badge.H{background:#243e5c;color:#d6e8ff}:root:not([data-theme="light"]) .badge.P{background:#1e3d3a;color:#c9efe4}:root:not([data-theme="light"]) .badge.T{background:#332848;color:#e4d4f5}:root:not([data-theme="light"]) .badge.A{background:#3d3424;color:#f3ddb4}:root:not([data-theme="light"]) .badge.U{background:#2a3340;color:#d5dee8}}

.theme-toggle{min-height:44px;padding:9px 13px;border:1px solid var(--line);border-radius:8px;font-size:12px;white-space:nowrap;color:var(--ink);background:var(--surface)}
:root .topbar,:root .catalog,:root dialog{background:var(--bar)}
:root h1,:root .record p,:root .target,:root #reader-body pre{color:var(--ink)}
:root .private,:root .compoundtype,:root .scopebox,:root .gap,:root .protocolbox{background:var(--panel);color:var(--ink);border-color:var(--line)}
:root .filtergroup select,:root #reader-controls select,:root .ref{background:var(--surface);color:var(--ink);border-color:var(--line)}
:root .pathbutton,:root .pathbutton.selected,:root .compoundrow.selected,:root .compoundrow:hover,:root .pathbutton:hover,:root .ref:hover,:root .iconbutton:hover{background:var(--pale);color:var(--ink);border-color:var(--line)}
:root .filterheading,:root .filter-note,:root .rowpath,:root .rowmeta,:root .detailpath,:root .cataloglabels,:root .tab,:root .matchnote,:root .strength,:root .sourcesview p,:root .empty,:root .source-status,:root footer,:root .protocolbox small,:root .gap strong,:root .edition{color:var(--muted)}
:root .context{color:var(--muted)!important}
:root .limitation{color:var(--muted)!important;border-color:var(--line)}
:root .review-banner{background:var(--panel);color:var(--ink);border-color:var(--line)}
:root .badge.H{background:#dce7f5;color:#163e6b}
:root .badge.P{background:#e3f3ef;color:#145248}
:root .badge.T{background:#efe6f6;color:#5a3474}
:root .badge.A{background:#f8efe3;color:#6d430c}
:root .badge.U{background:#e7edf3;color:#314150}
:root[data-theme="dark"] .badge.H{background:#243e5c;color:#d6e8ff}
:root[data-theme="dark"] .badge.P{background:#1e3d3a;color:#c9efe4}
:root[data-theme="dark"] .badge.T{background:#332848;color:#e4d4f5}
:root[data-theme="dark"] .badge.A{background:#3d3424;color:#f3ddb4}
:root[data-theme="dark"] .badge.U{background:#2a3340;color:#d5dee8}
:root .news-strip{background:var(--bar);color:var(--ink)}
:root .home-primary,:root .brandmark{background:var(--primary);color:var(--on-primary)}
:root input::placeholder{color:var(--muted)}
:root dialog::backdrop{background:#090f1bd9}
@media(max-width:900px){.theme-toggle{margin-left:auto;font-size:11px;padding:8px 10px}.topbar .private{margin-left:0}}
@media(max-width:600px){.topbar{column-gap:8px;display:grid;grid-template-columns:minmax(0,1fr) auto;grid-template-areas:"brand tools" "nav nav";height:auto;row-gap:4px;align-items:center}.topbar .brand{grid-area:brand}.topbar nav{grid-area:nav;order:0;width:100%;height:auto}.topbar-tools{grid-area:tools;margin-left:0;display:flex;align-items:center;gap:8px}.topbar .owner-ops{order:0}.topbar .private{display:none}.theme-toggle{font-size:12px}}

:root .brandmark span{color:#b9d4f7}
:root .detailtools button,:root .tab.active,:root .searchwrap svg{color:var(--green)}
:root .edition,:root .limitation,:root .pathbutton,:root .filtergroup select{border-color:var(--line)}
:root .status-dot{background:var(--green)}
:root button:focus-visible,:root a:focus-visible,:root input:focus-visible,:root select:focus-visible{outline-color:var(--green)}
.quick-filters,.active-filters{display:flex;align-items:center;flex-wrap:wrap;gap:8px;margin:12px 0}
.quick-label{font-size:12px;color:var(--muted);margin-right:4px}.filter-chip,.active-chip{display:inline-flex;align-items:center;gap:8px;min-height:44px;padding:9px 12px;border:1px solid var(--line);border-radius:24px;background:var(--surface);color:var(--ink);font-size:12px}.filter-chip span{font-size:11px;color:var(--muted)}.filter-chip[aria-pressed="true"],.active-chip{background:var(--pale);border-color:var(--green)}.filter-help{font-size:12px;color:var(--muted)}
.reading-controls{display:flex;gap:8px;align-items:center;flex-wrap:wrap;padding:12px 0;border-bottom:1px solid var(--line)}.reading-controls>span{font-size:12px;color:var(--muted)}.reading-controls button{font-size:12px;min-height:44px;padding:9px 12px;border:1px solid var(--line);border-radius:7px;background:var(--surface)}.reading-controls button[aria-pressed="true"]{background:var(--pale);border-color:var(--green)}
.compound-summary{margin:20px 0;padding:18px;border:1px solid var(--line);border-radius:10px;background:var(--surface)}.summary-heading{display:flex;justify-content:space-between;gap:12px;flex-wrap:wrap}.summary-heading strong{font-size:15px}.summary-heading>span{font-size:11px;color:var(--muted)}.summary-facts{margin:16px 0;display:grid;gap:12px}.summary-facts>div{display:grid;grid-template-columns:120px minmax(0,1fr);gap:12px}.summary-facts dt{font-size:12px;color:var(--muted)}.summary-facts dd{font-size:13px;line-height:1.7;margin:0;overflow-wrap:anywhere}.summary-evidence{display:flex;gap:12px;flex-wrap:wrap;align-items:center}.summary-evidence>span{display:flex;align-items:center;gap:5px;font-size:12px}.compound-summary>p{font-size:12px;line-height:1.8;color:var(--muted);margin:15px 0 0}
.detail-reading-nav{display:flex;justify-content:space-between;align-items:center;gap:12px;flex-wrap:wrap;background:var(--bg);border-bottom:1px solid var(--line);padding:8px 0;margin-bottom:18px}.detail-reading-nav button,.detail-reading-nav a{min-height:44px;display:inline-flex;align-items:center;font-size:12px}.detail-reading-nav a{text-decoration:none}
.detail .record{padding:20px 22px}.detail .record p{font-size:14px;line-height:1.85}.detail .record h3{font-size:18px;line-height:1.5}.detail .record .context{font-size:12px!important}.detail .matchnote{font-size:12px;line-height:1.8}.detail .gap{font-size:13px}.detail .target{font-size:14px}.detail .tab{min-height:44px;font-size:13px}.detail .ref{font-size:12px;min-height:44px}.detail .protocolbox{font-size:14px;padding:16px}.detail .protocol-fields dt{font-size:12px}.detail .protocol-fields dd{font-size:14px;line-height:1.75}.protocol-status{display:flex;gap:8px;align-items:center;flex-wrap:wrap}.protocol-status small{margin:0}.protocol-more{border-top:1px solid var(--line);margin-top:14px;padding-top:6px}.protocol-more summary{min-height:44px;padding:12px 0;cursor:pointer;font-size:13px;font-weight:600;color:var(--green)}.protocol-essential{margin-bottom:8px}.protocol-more .protocol-verification{line-height:1.8}
:root[data-reading="large"] .detail .record p,:root[data-reading="large"] .detail .protocol-fields dd,:root[data-reading="large"] .detail .protocolbox,:root[data-reading="large"] .summary-facts dd{font-size:17px}:root[data-reading="large"] .detail .record h3{font-size:21px}:root[data-reading="large"] .detail .context{font-size:14px!important}
:root[data-density="compact"] .detail .record{padding:12px 14px}:root[data-density="compact"] .compound-summary{padding:12px}:root[data-density="compact"] .detail .protocolbox{padding:12px}:root[data-density="compact"] .summary-facts{gap:6px}
@media(max-width:900px){.detail-reading-nav{position:sticky;top:0;z-index:4;padding:6px 0}.detail{scroll-margin-top:12px}.detail .tabs{position:sticky;top:63px;z-index:3;background:var(--bg);padding-top:8px}.detail .record p{font-size:16px}.summary-facts>div{grid-template-columns:1fr;gap:3px}.summary-heading strong{font-size:16px}.summary-facts dd{font-size:15px}.compound-summary{padding:16px}.detail .protocol-fields dd{font-size:16px}.filter-chip{font-size:13px}.reading-controls{gap:6px}.detail .record .context{font-size:13px!important}}
@media(prefers-reduced-motion:reduce){html{scroll-behavior:auto}}
@media(max-width:600px){.detail .record{padding:16px}}
.summary-facts .regulatory-note{display:block;margin-top:6px}

/* Atlas navigation: links and buttons share identical header geometry. */
.topbar nav{display:flex;align-items:stretch;min-width:0}
.topbar nav > .navitem{box-sizing:border-box;display:flex!important;align-items:center!important;justify-content:center!important;position:relative;top:0!important;align-self:stretch!important;height:auto!important;min-height:44px;line-height:1.25!important;padding:0 1px!important;margin:0!important;text-decoration:none!important;white-space:nowrap;flex:0 0 auto}
@media(max-width:900px){.topbar nav > .navitem{height:44px!important;align-self:center!important}}
/* "Get the App" feature link on the public home page (public-edition/get-app.js). */
.get-app{--glow:#4f8fd6;position:relative;display:inline-flex;align-items:center;gap:12px;margin-top:18px;padding:10px 18px 10px 12px;min-height:44px;border-radius:999px;color:var(--on-primary);text-decoration:none;background:linear-gradient(120deg,#285e99,#3f7fc4 45%,#1d7566);background-size:220% 100%;box-shadow:0 4px 18px rgba(40,94,153,.35);isolation:isolate;animation:get-app-sheen 6s ease-in-out infinite;transition:transform .2s ease,box-shadow .2s ease}
.get-app::before{content:"";position:absolute;inset:-3px;z-index:-1;border-radius:inherit;background:var(--glow);opacity:.45;filter:blur(8px);animation:get-app-pulse 2.6s ease-in-out infinite}
.get-app:hover,.get-app:focus-visible{transform:translateY(-2px);box-shadow:0 8px 24px rgba(40,94,153,.45)}
.get-app[hidden]{display:none}
.get-app:focus-visible{outline:3px solid var(--green);outline-offset:3px}
.get-app-new{padding:3px 8px;border-radius:999px;background:#f3c969;color:#2b2210;font-size:11px;font-weight:800;letter-spacing:.08em;text-transform:uppercase;animation:get-app-pop 2.6s ease-in-out infinite}
.get-app-icon{display:inline-flex;width:28px;height:28px;align-items:center;justify-content:center;border-radius:8px;background:rgba(255,255,255,.16)}
.get-app-icon svg{width:16px;height:16px}
.get-app-text{display:flex;flex-direction:column;line-height:1.2}
.get-app-text strong{font-size:16px}
.get-app-text small{font-size:12px;opacity:.88}
.get-app-arrow{font-size:18px;transition:transform .2s ease}
.get-app:hover .get-app-arrow,.get-app:focus-visible .get-app-arrow{transform:translateX(4px)}
@keyframes get-app-sheen{0%,100%{background-position:0% 50%}50%{background-position:100% 50%}}
@keyframes get-app-pulse{0%,100%{opacity:.25;transform:scale(.98)}50%{opacity:.6;transform:scale(1.03)}}
@keyframes get-app-pop{0%,80%,100%{transform:scale(1)}88%{transform:scale(1.15)}}
@media(prefers-reduced-motion:reduce){.get-app,.get-app::before,.get-app-new{animation:none}.get-app,.get-app-arrow{transition:none}}
@media(max-width:900px){.get-app{display:flex;width:100%;box-sizing:border-box;margin-top:16px}.get-app-arrow{margin-left:auto}}

/* Cycle 10: invite the next visit after the research, with clear platform choices. */
.install-invitation{display:grid;grid-template-columns:1.3fr 1fr;gap:48px;align-items:center;margin:28px 0 36px;padding:clamp(26px,5vw,60px);border-radius:4px 24px 24px 24px;background:var(--panel);border:1px solid var(--line);overflow:hidden}.install-invitation h2{font:clamp(34px,4vw,54px)/1.12 Georgia,serif;letter-spacing:-1px;margin:16px 0 20px}.install-invitation h2 em{color:var(--green);font-weight:400}.install-invitation p{font-size:15px;line-height:1.8;color:var(--muted);max-width:580px}.install-invitation>div>small{display:block;font-size:12px;color:var(--muted);line-height:1.7;margin-top:18px}.install-actions{display:flex;gap:12px;flex-wrap:wrap;margin-top:24px}.install-actions a{display:inline-flex;align-items:center;gap:18px;min-height:48px;padding:14px 18px;border:1px solid var(--green);border-radius:8px;text-decoration:none;font-size:13px;font-weight:650}.install-actions a:first-child{background:var(--primary);color:var(--on-primary)}.install-art{display:flex;justify-content:center;transform:rotate(4deg)}.install-art-card{width:260px;padding:28px;border:1px solid #7295ae;border-radius:22px;background:#102a43;color:#edf7ff;box-shadow:18px 18px 0 #102a4318}.install-art-card>span{font-size:10px;letter-spacing:2px;color:#a6dfce}.install-art-card>strong{display:block;font:31px/1.2 Georgia,serif;margin:28px 0}.install-art-card>div{display:flex;justify-content:space-between;padding:14px 0;border-top:1px solid #456079;font-size:13px}.install-art-card b{color:#a6dfce}@media(max-width:700px){.install-invitation{grid-template-columns:1fr;gap:26px}.install-actions{flex-direction:column}.install-actions a{justify-content:space-between}.install-art-card{width:100%}.install-art{transform:rotate(0)}.install-art-card>strong{font-size:28px}}